期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 141, 期 51, 页码 20058-20061出版社
AMER CHEMICAL SOC
DOI: 10.1021/jacs.9b12315
关键词
-
资金
- Pfizer Inc.
- Bristol-Myers Squibb
A new and practical method has been developed for the transformation of racemic alpha-bromo ketones to chiral alpha-azido and alpha-amino ketones with high enantioselectivity using phase transfer, ion-pair mediated reactions with a recoverable chiral quaternary salt (10 mol %) as catalyst in fluorobenzene-water. The process has been generalized to a variety of other attachments including of C, O, S, and NHR.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据