4.2 Article

MicroRNA hsa-miR-4674 in Hemolysis-Free Blood Plasma Is Associated with Distant Metastases of Prostatic Cancer

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SPRINGER
DOI: 10.1007/s10517-016-3358-6

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microRNA; prostatic cancer; metastases; microarray analysis; blood plasma

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  1. Federal Target Program Research and Development in Priority Areas of Development of the Russian Scientific and Technolo-gical Complex [RFME-FI57914X0054]

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We analyzed microRNA profile in hemolysis-free blood plasma of patients with prostatic cancer. The metastatic form of prostatic cancer was found to be associated with increased levels of hsa-miR-22-3p, hsa-miR-663a, and hsa-miR-4674 in comparison with non-metastatic form. Common candidate target genes of these microRNA include JUNB, KMT2A, and XPO6.

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