期刊
BIOSCIENCE
卷 65, 期 11, 页码 1046-1056出版社
OXFORD UNIV PRESS
DOI: 10.1093/biosci/biv139
关键词
lamprey; genomics; evolution; molecular mechanisms; control
类别
Lampreys, one of the two surviving groups of ancient vertebrates, have become important models for study in diverse fields of biology Lampreys (of which there are approximately 40 species) are being studied, for example, (a) to control pest sea lamprey in the North American Great Lakes and to restore declining populations of native species elsewhere; (b) in biomedical research, focusing particularly on the regenerative capability of lampreys; and (c) by developmental biologists studying the evolution of key vertebrate characters. Although a lack of genetic resources has hindered research on the mechanisms regulating many aspects of lamprey life history and development, formerly intractable questions are now amenable to investigation following the recent publication of the sea lamprey genome. Here, we provide an overview of the ways in which genomic tools are currently being deployed to tackle diverse research questions and suggest several areas that may benefit from the availability of the sea lamprey genome.
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