相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Identification of compounds inhibiting prion replication and toxicity by removing PrP© from the cell surface
Silvia Biggi et al.
JOURNAL OF NEUROCHEMISTRY (2020)
Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression
Samia Hannaoui et al.
JOURNAL OF NEUROCHEMISTRY (2020)
Experimental models to study prion disease pathogenesis and identify potential therapeutic compounds
Ina Vorberg et al.
CURRENT OPINION IN PHARMACOLOGY (2019)
Engineering a murine cell line for the stable propagation of hamster prions
Matthew E. C. Bourkas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Full restoration of specific infectivity and strain properties from pure mammalian prion protein
Cassandra Burke et al.
PLOS PATHOGENS (2019)
Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development
Sonia M. Vallabh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Age at onset in genetic prion disease and the design of preventive clinical trials
Eric Vallabh Minikel et al.
NEUROLOGY (2019)
Primary structural differences at residue 226 of deer and elk PrP dictate selection of distinct CWD prion strains in gene-targeted mice
Jifeng Bian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Gene-edited murine cell lines for propagation of chronic wasting disease prions
Rupali Walia et al.
SCIENTIFIC REPORTS (2019)
Full atomistic model of prion structure and conversion
Giovanni Spagnolli et al.
PLOS PATHOGENS (2019)
Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids
Bradley R. Groveman et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)
Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy
Antonio Heras-Garvin et al.
MOVEMENT DISORDERS (2019)
Variable Protease-Sensitive Prionopathy Transmission to Bank Voles
Romolo Nonno et al.
EMERGING INFECTIOUS DISEASES (2019)
Antisense oligonucleotides extend survival of prion-infected mice
Gregory J. Raymond et al.
JCI INSIGHT (2019)
Prions, prionoids and protein misfolding disorders
Claudia Scheckel et al.
NATURE REVIEWS GENETICS (2018)
The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling
Farinaz Ghodrati et al.
SCIENTIFIC REPORTS (2018)
Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases
Claudio Soto et al.
NATURE NEUROSCIENCE (2018)
A Bioluminescent Cell Assay to Quantify Prion Protein Dimerization
Katharina Annick Wuesten et al.
SCIENTIFIC REPORTS (2018)
Prions activate a p38 MAPK synaptotoxic signaling pathway
Cheng Fang et al.
PLOS PATHOGENS (2018)
British man with CJD gets experimental treatment in world first
Clare Dyer
BMJ-BRITISH MEDICAL JOURNAL (2018)
Novel Type of Chronic Wasting Disease Detected in Moose (Alces alces), Norway
Laura Pirisinu et al.
EMERGING INFECTIOUS DISEASES (2018)
Prion Disease in Dromedary Camels, Algeria
Baaissa Babelhadj et al.
EMERGING INFECTIOUS DISEASES (2018)
The function of the cellular prion protein in health and disease
Joel C. Watts et al.
ACTA NEUROPATHOLOGICA (2018)
Cofactors influence the biological properties of infectious recombinant prions
Natalia Fernandez-Borges et al.
ACTA NEUROPATHOLOGICA (2018)
Pharmacological Agents Targeting the Cellular Prion Protein
Maria Letizia Barreca et al.
PATHOGENS (2018)
Doxycycline in early CJD: a double-blinded randomised phase II and observational study
Daniela Varges et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2017)
PrP Knockout Cells Expressing Transmembrane PrP Resist Prion Infection
Karen E. Marshall et al.
JOURNAL OF VIROLOGY (2017)
Insights from Therapeutic Studies for PrP Prion Disease
Kenta Teruya et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner
Zuzana Krejciova et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease
Christina D. Orru et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Role of the central lysine cluster and scrapie templating in the transmissibility of synthetic prion protein aggregates
Bradley R. Groveman et al.
PLOS PATHOGENS (2017)
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity
Tania Massignan et al.
CHEMMEDCHEM (2017)
Prion disease: experimental models and reality
Sebastian Brandner et al.
ACTA NEUROPATHOLOGICA (2017)
Diagnostic and prognostic value of human prion detection in cerebrospinal fluid
Aaron Foutz et al.
ANNALS OF NEUROLOGY (2017)
Identification of Anti-prion Compounds using a Novel Cellular Assay
Thibaut Imberdis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
PrPC Governs Susceptibility to Prion Strains in Bank Vole, While Other Host Factors Modulate Strain Features
J. C. Espinosa et al.
JOURNAL OF VIROLOGY (2016)
A transfectant RK13 cell line permissive to classical caprine scrapie prion propagation
Rohana P. Dassanayake et al.
PRION (2016)
Quantifying prion disease penetrance using large population control cohorts
Eric Vallabh Minikel et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease
Luis Concha-Marambio et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Gerstmann-Straussler-Scheinker disease subtypes efficiently transmit in bank voles as genuine prion diseases
Laura Pirisinu et al.
SCIENTIFIC REPORTS (2016)
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein
Tania Massignan et al.
SCIENTIFIC REPORTS (2016)
A Neuronal Culture System to Detect Prion Synaptotoxicity
Cheng Fang et al.
PLOS PATHOGENS (2016)
A Single Subcutaneous Injection of Cellulose Ethers Administered Long before Infection Confers Sustained Protection against Prion Diseases in Rodents
Kenta Teruya et al.
PLOS PATHOGENS (2016)
The Structural Architecture of an Infectious Mammalian Prion Using Electron Cryomicroscopy
Ester Vazquez-Fernandez et al.
PLOS PATHOGENS (2016)
Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
Kurt Giles et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)
Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies
Jens Wagner et al.
ACTA NEUROPATHOLOGICA (2015)
Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice
David Berry et al.
JOURNAL OF INFECTIOUS DISEASES (2015)
Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains
Camilo Duque Velasquez et al.
JOURNAL OF VIROLOGY (2015)
Structure-based drug design identifies polythiophenes as antiprion compounds
Uli S. Herrmann et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
hTERT-immortalized ovine microglia propagate natural scrapie isolates
Juan F. Munoz-Gutierrez et al.
VIRUS RESEARCH (2015)
The Standard Scrapie Cell Assay: Development, Utility and Prospects
Jacques van der Merwe et al.
VIRUSES-BASEL (2015)
Prion Infections and Anti-PrP Antibodies Trigger Converging Neurotoxic Pathways
Uli S. Herrmann et al.
PLOS PATHOGENS (2015)
A Bovine Cell Line That Can Be Infected by Natural Sheep Scrapie Prions
Anja M. Oelschlegel et al.
PLOS ONE (2015)
Generation of a Persistently Infected MDBK Cell Line with Natural Bovine Spongiform Encephalopathy (BSE)
Dongseob Tark et al.
PLOS ONE (2015)
Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains
Kurt Giles et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Piperazine derivatives inhibit PrP/PrPres propagation in vitro and in vivo
Fabienne Leidel et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells
B. Michael Silber et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
Identification of a gene regulatory network associated with prion replication
Masue M. Marbiah et al.
EMBO JOURNAL (2014)
Mouse Models for Studying the Formation and Propagation of Prions
Joel C. Watts et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Cycline Efficacy on the Propagation of Human Prions in Primary Cultured Neurons is Strain-Specific
Samia Hannaoui et al.
JOURNAL OF INFECTIOUS DISEASES (2014)
Postmortem findings in a case of variant Creutzfeldt-Jakob disease treated with intraventricular pentosan polysulfate
P. K. Newman et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2014)
Doxycycline in Creutzfeldt-Jakob disease: a phase 2, randomised, double-blind, placebo-controlled trial
Stephane Haik et al.
LANCET NEUROLOGY (2014)
A Test for Creutzfeldt-Jakob Disease Using Nasal Brushings
Christina D. Orru et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Prions in the Urine of Patients with Variant Creutzfeldt- Jakob Disease
Fabio Moda et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Systemic Delivery of siRNA Down Regulates Brain Prion Protein and Ameliorates Neuropathology in Prion Disorder
Sylvain Lehmann et al.
PLOS ONE (2014)
The many shades of prion strain adaptation
Ilia V. Baskakov
PRION (2014)
Quinacrine promotes replication and conformational mutation of chronic wasting disease prions
Jifeng Bian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Evidence That Bank Vole PrP Is a Universal Acceptor for Prions
Joel C. Watts et al.
PLOS PATHOGENS (2014)
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease
Jens Wagner et al.
ACTA NEUROPATHOLOGICA (2013)
Antiprion compounds that reduce PrPSc levels in dividing and stationary-phase cells
B. Michael Silber et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Prion Propagation and Toxicity Occur In Vitro with Two-Phase Kinetics Specific to Strain and Neuronal Type
Samia Hannaoui et al.
JOURNAL OF VIROLOGY (2013)
Prion Replication Elicits Cytopathic Changes in Differentiated Neurosphere Cultures
Yoshifumi Iwamaru et al.
JOURNAL OF VIROLOGY (2013)
The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein
Tiziana Sonati et al.
NATURE (2013)
Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease
Michael D. Geschwind et al.
NEUROLOGY (2013)
Early Increase and Late Decrease of Purkinje Cell Dendritic Spine Density in Prion-Infected Organotypic Mouse Cerebellar Cultures
Jody L. Campeau et al.
PLOS ONE (2013)
Pharmacokinetics and Metabolism of 2-Aminothiazoles with Antiprion Activity in Mice
B. Michael Silber et al.
PHARMACEUTICAL RESEARCH (2013)
Drug resistance confounding prion therapeutics
David B. Berry et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Unique drug screening approach for prion diseases identifies tacrolimus and astemizole as antiprion agents
Yervand Eduard Karapetyan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
Julie A. Moreno et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Cellular Aspects of Prion Replication In Vitro
Andrea Grassmann et al.
VIRUSES-BASEL (2013)
Infectious Prions Accumulate to High Levels in Non Proliferative C2C12 Myotubes
Allen Herbst et al.
PLOS PATHOGENS (2013)
Acquisition of Drug Resistance and Dependence by Prions
Anja M. Oelschlegel et al.
PLOS PATHOGENS (2013)
The Evolution of Transmissible Prions: The Role of Deformed Templating
Natallia Makarava et al.
PLOS PATHOGENS (2013)
Biaryl Amides and Hydrazones as Therapeutics for Prion Disease in Transgenic Mice
Duo Lu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2013)
Polythiophenes Inhibit Prion Propagation by Stabilizing Prion Protein (PrP) Aggregates
Ilan Margalith et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A Brain Aggregate Model Gives New Insights Into the Pathobiology and Treatment of Prion Diseases
Krystyna Bajsarowicz et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2012)
Establishment of a Cell Line Persistently Infected with Chronic Wasting Disease Prions
Hyo-Jin Kim et al.
JOURNAL OF VETERINARY MEDICAL SCIENCE (2012)
The Extended Cell Panel Assay Characterizes the Relationship of Prion Strains RML, 79A, and 139A and Reveals Conversion of 139A to 79A-Like Prions in Cell Culture
Anja M. Oelschlegel et al.
JOURNAL OF VIROLOGY (2012)
Strain-Specific Role of RNAs in Prion Replication
Paula Saa et al.
JOURNAL OF VIROLOGY (2012)
Sustained translational repression by eIF2α-P mediates prion neurodegeneration
Julie A. Moreno et al.
NATURE (2012)
The Toxicity of a Mutant Prion Protein Is Cell-Autonomous, and Can Be Suppressed by Wild-Type Prion Protein on Adjacent Cells
Emiliano Biasini et al.
PLOS ONE (2012)
Cell-specific susceptibility to prion strains is a property of the intact cell
Maria E. Herva et al.
PRION (2012)
Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids
Nathan R. Deleault et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Cofactor molecules maintain infectious conformation and restrict strain properties in purified prions
Nathan R. Deleault et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Prion Pathogenesis Is Faithfully Reproduced in Cerebellar Organotypic Slice Cultures
Jeppe Falsig et al.
PLOS PATHOGENS (2012)
Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice
Karah Nazor Friberg et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2012)
Healthy goats naturally devoid of prion protein
Sylvie L. Benestad et al.
VETERINARY RESEARCH (2012)
latrogenic Creutzfeldt-Jakob Disease, Final Assessment
Paul Brown et al.
EMERGING INFECTIOUS DISEASES (2012)
2-Aminothiazoles as Therapeutic Leads for Prion Diseases
Alejandra Gallardo-Godoy et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Rapid cell-surface prion protein conversion revealed using a novel cell system
R. Goold et al.
NATURE COMMUNICATIONS (2011)
Human Prion Strain Selection in Transgenic Mice
Kurt Giles et al.
ANNALS OF NEUROLOGY (2010)
Variably Protease-Sensitive Prionopathy: A New Sporadic Disease of the Prion Protein
Wen-Quan Zou et al.
ANNALS OF NEUROLOGY (2010)
Species-Dependent Differences in Cofactor Utilization for Formation of the Protease-Resistant Prion Protein in Vitro
Nathan R. Deleault et al.
BIOCHEMISTRY (2010)
A Novel, Drug-based, Cellular Assay for the Activity of Neurotoxic Mutants of the Prion Protein
Tania Massignan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Conservation of a Glycine-rich Region in the Prion Protein Is Required for Uptake of Prion Infectivity
Christopher F. Harrison et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Prion infection of differentiated neurospheres
Maria Eugenia Herva et al.
JOURNAL OF NEUROSCIENCE METHODS (2010)
Infection of Cell Lines with Experimental and Natural Ovine Scrapie Agents
Michael H. Neale et al.
JOURNAL OF VIROLOGY (2010)
Discovery of 2-Aminothiazoles as Potent Antiprion Compounds
Sina Ghaemmaghami et al.
JOURNAL OF VIROLOGY (2010)
Cell-Based Quantification of Chronic Wasting Disease Prions
Jifeng Bian et al.
JOURNAL OF VIROLOGY (2010)
Defining sporadic Creutzfeldt-Jakob disease strains and their transmission properties
Matthew T. Bishop et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Darwinian Evolution of Prions in Cell Culture
Jiali Li et al.
SCIENCE (2010)
Prion Strain Mutation and Selection
John Collinge
SCIENCE (2010)
Prion Strain Mutation Determined by Prion Protein Conformational Compatibility and Primary Structure
Rachel C. Angers et al.
SCIENCE (2010)
Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays
Jason M. Wilham et al.
PLOS PATHOGENS (2010)
Autophagy induction by trehalose counteracts cellular prion infection
Yasmine Aguib et al.
AUTOPHAGY (2009)
Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy
Andreas Heiseke et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Cells Expressing Anchorless Prion Protein Are Resistant to Scrapie Infection
Kristin L. McNally et al.
JOURNAL OF VIROLOGY (2009)
Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial
John Collinge et al.
LANCET NEUROLOGY (2009)
Continuous intraventricular infusion of pentosan polysulfate: Clinical trial against prion diseases
Yoshio Tsuboi et al.
NEUROPATHOLOGY (2009)
The Comprehensive Native Interactome of a Fully Functional Tagged Prion Protein
Dorothea Rutishauser et al.
PLOS ONE (2009)
Interactome Analyses Identify Ties of PrPC and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones
Joel C. Watts et al.
PLOS PATHOGENS (2009)
Continuous Quinacrine Treatment Results in the Formation of Drug-Resistant Prions
Sina Ghaemmaghami et al.
PLOS PATHOGENS (2009)
CRBL cells: Establishment, characterization and susceptibility to prion infection
Charles E. Mays et al.
BRAIN RESEARCH (2008)
Intraventricular pentosan polysulphate in human prion disease: An observational study in the UK
I. Bone et al.
EUROPEAN JOURNAL OF NEUROLOGY (2008)
Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture
Victoria A. Lawson et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
Prions impair bioaminergic functions through serotonin- or catecholamine-derived neurotoxins in neuronal cells
Sophie Mouillet-Richard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A cell line infectible by prion strains from different species
M. -P. Courageot et al.
JOURNAL OF GENERAL VIROLOGY (2008)
The prion organotypic slice culture assay - POSCA
Jeppe Falsig et al.
NATURE PROTOCOLS (2008)
The Efficacy of Tetracyclines in Peripheral and Intracerebral Prion Infection
Ada De Luigi et al.
PLOS ONE (2008)
Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease
Melanie D. White et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
BSE case associated with prion protein gene mutation
Jurgen A. Richt et al.
PLOS PATHOGENS (2008)
Resistance of Bovine Spongiform Encephalopathy (BSE) Prions to Inactivation
Kurt Giles et al.
PLOS PATHOGENS (2008)
A versatile prion replication assay in organotypic brain slices
Jeppe Falsig et al.
NATURE NEUROSCIENCE (2008)
Prion strain discrimination in cell culture: The cell panel assay
Sukhvir P. Mahal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Selective incorporation of polyanionic molecules into hamster prions
James C. Geoghegan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Orally administered amyloidophilic compound is effective in prolonging the incubation periods of animals cerebrally infected with prion diseases in a prion strain-dependent manner
Yuri Kawasaki et al.
JOURNAL OF VIROLOGY (2007)
Prion strain- and species-dependent effects of antiprion molecules in primary neuronal cultures
Sabrina Cronier et al.
JOURNAL OF VIROLOGY (2007)
Cell division modulates prion accumulation in cultured cells
Sina Ghaemmaghami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A general model of prion strains and their pathogenicity
John Collinge et al.
SCIENCE (2007)
Long term survival in a patient with variant Creutzfeldt-Jakob disease treated with intraventricular pentosan polysulphate
A. Parry et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2007)
Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins
Elke Maas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Formation of native prions from minimal components in vitro
Nathan R. Deleault et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Prion infection of muscle cells in vitro
Wendy M. Dlakic et al.
JOURNAL OF VIROLOGY (2007)
Targeting cellular prion protein reverses early coanitive deficits and neurophysiological dysfunction in prion-infected mice
Giovanna R. Mallucci et al.
NEURON (2007)
Microglial cell line established from prion protein-overexpressing mice is susceptible to various murine prion strains
Yoshifumi Iwamaru et al.
JOURNAL OF VIROLOGY (2007)
Production of cattle lacking prion protein
Jurgen A. Richt et al.
NATURE BIOTECHNOLOGY (2007)
The prion protein family: Diversity, rivalry, and dysfunction
Joel C. Watts et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2007)
Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice
Alexander Pfeifer et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Kuru in the 21st century - an acquired human prion disease with very long incubation periods
John Collinge et al.
LANCET (2006)
Predicting susceptibility and incubation time of human-to-human transmission of vCJD
MT Bishop et al.
LANCET NEUROLOGY (2006)
Prion infection of mouse neurospheres
RK Giri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The expanding universe of prion diseases
Joel C. Watts et al.
PLOS PATHOGENS (2006)
Mouse-adapted scrapie infection of SN56 cells: Greater efficiency with microsome-associated versus purified PrP-res
GS Baron et al.
JOURNAL OF VIROLOGY (2006)
Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles
Romolo Nonno et al.
PLOS PATHOGENS (2006)
Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting disease
GJ Raymond et al.
JOURNAL OF VIROLOGY (2006)
A systematic review of prion therapeutics in experimental models
Clare R. Trevitt et al.
BRAIN (2006)
Reciprocal interference between specific CJD and scrapie agents in neural cell cultures
N Nishida et al.
SCIENCE (2005)
Prion clearance in bigenic mice
JG Safar et al.
JOURNAL OF GENERAL VIROLOGY (2005)
In vitro generation of infectious scrapie prions
J Castilla et al.
CELL (2005)
Treatment of transmissible spongiform encephalopathy by intraventricular drug infusion in animal models
K Doh-Ura et al.
JOURNAL OF VIROLOGY (2004)
Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents
I Vorberg et al.
JOURNAL OF INFECTIOUS DISEASES (2004)
Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death
S Cronier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Genetic mapping of activity determinants within cellular prion proteins -: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B′ region
B Drisaldi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Acute formation of protease-resistant prion protein does not always lead to persistent scrapie infection in vitro
I Vorberg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Intrinsic resistance of oligodendrocytes to prion infection
M Prinz et al.
JOURNAL OF NEUROSCIENCE (2004)
Two Creutzfeldt-Jakob disease agents reproduce prion protein-independent identities in cell cultures
A Arjona et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues
G Schmitt-Ulms et al.
NATURE BIOTECHNOLOGY (2004)
Cultured peripheral neuroglial cells are highly permissive to sheep prion infection
F Archer et al.
JOURNAL OF VIROLOGY (2004)
Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis
G Mallucci et al.
SCIENCE (2003)
RNA molecules stimulate prion protein conversion
NR Deleault et al.
NATURE (2003)
New inhibitors of scrapie-associated prion protein formation in a library of 2,000 drugs and natural products
DA Kocisko et al.
JOURNAL OF VIROLOGY (2003)
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions
PC Klöhn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Cases of scrapie with unusual features in Norway and designation of a new type, Nor98
SL Benestad et al.
VETERINARY RECORD (2003)
Evaluation of quinacrine treatment for prion diseases
A Barret et al.
JOURNAL OF VIROLOGY (2003)
Efficient and specific down-regulation of prion protein expression by RNAi
G Tilly et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Inhibition of protease-resistant prion protein accumulation in vitro by curcumin
B Caughey et al.
JOURNAL OF VIROLOGY (2003)
Potent inhibition of scrapie prion replication in cultured cells by bis-acridines
BCH May et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Monoclonal antibodies inhibit prion replication and delay the development of prion disease
AR White et al.
NATURE (2003)
PrP Polymorphisms tightly control sheep prion replication in cultured cells
E Sabuncu et al.
JOURNAL OF VIROLOGY (2003)
Quinacrine does not prolong survival in a murine Creutzfeldt-Jakob disease model
SJ Collins et al.
ANNALS OF NEUROLOGY (2002)
Tetracyclines affect prion infectivity
G Forloni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
A change in the conformation of prions accompanies the emergence of a new prion strain
D Peretz et al.
NEURON (2002)
PrP expression and replication by Schwann cells: Implications in prion spreading
J Follet et al.
JOURNAL OF VIROLOGY (2002)
Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies
FL Heppner et al.
SCIENCE (2001)
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity
D Peretz et al.
NATURE (2001)
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease
C Korth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
M Enari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Scrapie strains maintain biological phenotypes on propagation in a cell line in culture
CR Birkett et al.
EMBO JOURNAL (2001)
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
GP Saborio et al.
NATURE (2001)
Branched polyamines cure prion-infected neuroblastoma cells
S Supattapone et al.
JOURNAL OF VIROLOGY (2001)
Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein
D Vilette et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Cultured cell sublines highly susceptible to prion infection
PJ Bosque et al.
JOURNAL OF VIROLOGY (2000)
Amphotericin B inhibits the generation of the scrapie isoform of the prion protein in infected cultures
A Mangé et al.
JOURNAL OF VIROLOGY (2000)
Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation
K Doh-Ura et al.
JOURNAL OF VIROLOGY (2000)
Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein
N Nishida et al.
JOURNAL OF VIROLOGY (2000)