期刊
JOURNAL OF MEDICAL VIROLOGY
卷 92, 期 5, 页码 491-494出版社
WILEY
DOI: 10.1002/jmv.25709
关键词
coronavirus; immnopathology; immune responses; pathogenesis; respiratory tract; virus classification
类别
资金
- National Scientific and Technological Major Project of China [2017ZX10202203]
- National Natural Science Foundation of China [81861138044, 91742114, 91642118]
First reported from Wuhan, The People's Republic of China, on 31 December 2019, the ongoing outbreak of a novel coronavirus (2019-nCoV) causes great global concerns. Based on the advice of the International Health Regulations Emergency Committee and the fact that to date 24 other countries also reported cases, the WHO Director-General declared that the outbreak of 2019-nCoV constitutes a Public Health Emergency of International Concern on 30 January 2020. Together with the other two highly pathogenic coronaviruses, the severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), 2019-nCov and other yet to be identified coronaviruses pose a global threat to public health. In this mini-review, we provide a brief introduction to the pathology and pathogenesis of SARS-CoV and MERS-CoV and extrapolate this knowledge to the newly identified 2019-nCoV.
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