期刊
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
卷 34, 期 23, 页码 3867-3873出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14767058.2019.1701648
关键词
End-diastolic flow; fetal growth discordance; laser surgery; preterm; twin-twin transfusion syndrome; umbilical artery Doppler
This retrospective study investigated the antenatal course of 48 monochorionic diamniotic twins with selective intrauterine growth restriction (SIUGR) type III. The study found that approximately half of the patients progressed during the antenatal period, with the lack of progression being associated with a higher dual survivorship rate. Dual survivorship was significantly lower in the group that progressed compared to the group that did not progress.
Objective: To describe the antenatal course of selective intrauterine growth restriction (SIUGR) type III patients. Study design: Retrospective study of monochorionic diamniotic twins with SIUGR type III. Patients were divided into those who did and did not progress to SIUGR type II or twin-twin transfusion syndrome (TTTS) (Groups A and B, respectively). Patient characteristics and perinatal survival were compared by Group, and continuous data are reported as median (range). Results: Forty-eight patients were studied; Group A [26 (54.2%)] and Group B [22 (45.8%)]. The difference in 30-day survivorship for the appropriate for gestational age twin (88.5 vs. 100%, p = .2394) and for the SIUGR twin (73.1 vs. 95.5%, p = .0551) was not statistically significant. However, dual survivorship was lower in Group A compared to Group B (69.2 vs. 95.4%, p = .0276). Conclusions: Approximately half of the SIUGR type III patients had antenatal progression. Lack of antenatal progression was associated with 95% dual survivorship. Rationale: The antenatal course of monochorionic diamniotic twins complicated by SIUGR type III is not well-understood and antenatal management remains a clinical dilemma. We provide pregnancy outcomes in a referred group of SIUGR type III patients, including the rate of progression to SIUGR type II and TTTS.
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