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Quantitative Susceptibility Mapping: Technical Considerations and Clinical Applications in Neuroimaging

期刊

JOURNAL OF MAGNETIC RESONANCE IMAGING
卷 53, 期 1, 页码 23-37

出版社

WILEY
DOI: 10.1002/jmri.27058

关键词

quantitative susceptibility mapping; clinical applications; iron quantification; venous oxygen saturation

资金

  1. Science and Engineering Research Board (SERB), Department of Science and Technology (DST) [PDF/2016/001493]
  2. GE Healthcare

向作者/读者索取更多资源

Quantitative susceptibility mapping (QSM) is a novel MRI technique used to study magnetic susceptibility and oxygen metabolism in the brain, serving as imaging biomarkers for neurological diseases with wide clinical applications and potential.
Quantitative susceptibility mapping (QSM) is a novel magnetic resonance imaging (MRI) technique for quantifying the spatial distribution of magnetic susceptibility within an object or tissue. Recently, QSM has been widely used to study various dominant magnetic susceptibility sources in the brain, including iron and calcium. In addition, the method enables mapping of the cerebral metabolic rate of oxygen, which could act as a new metabolic biomarker for diseases that involve disruption of the brain's oxygen supply. Thus, the clinical applications of QSM are wide-reaching and hold great promise as imaging biomarkers for studying several neurological diseases. This review aims to summarize the physical concepts and potential clinical applications of QSM in neuroimaging. Evidence Level: 5 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2020.

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