期刊
JOURNAL OF BONE AND MINERAL METABOLISM
卷 38, 期 2, 页码 141-144出版社
SPRINGER JAPAN KK
DOI: 10.1007/s00774-020-01087-0
关键词
Aromatase inhibitor; Androgen deprivation therapy; Fracture; Bone mineral density
Androgen deprivation therapy and aromatase inhibitors are known to cause a decrease in bone mineral density and an increase in fractures. Patients receiving these treatments have been shown to have a fracture risk equal to or greater than that of patients with osteoporosis with prevalent fractures. This manual was created to prevent fractures in patients with cancer treatment-induced bone loss with high fracture risks who cannot be treated under the current Japanese guideline for the prevention and treatment of osteoporosis. This manual recommends drug treatment for patients with BMD - 2.0 <= T score T score < - 2.0. It is important to verify whether the use of this manual can reduce fractures and improve the quality of life of patients with cancer treatment-induced bone loss by prospective studies.
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