4.7 Article

Structural dynamics of inosine triphosphate pyrophosphatase (ITPA) protein and two clinically relevant mutants: molecular dynamics simulations

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Effect of thermostable mutations on the neurotensin receptor 1 (NTSR1) activation state

Shanthi Nagarajan et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2020)

Article Biochemistry & Molecular Biology

Studying the collective motions of the adenosine A2A receptor as a result of ligand binding using principal component analysis

Marlet Martinez-Archundia et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2019)

Article Biochemistry & Molecular Biology

Structural insight into the binding mechanism of ATP to EGFR and L858R, and T790M and L858R/T790 mutants

Lucia Saldana-Rivera et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2019)

Article Biochemistry & Molecular Biology

An insight into the binding of 6-hydroxyflavone with hen egg white lysozyme: a combined approach of multi-spectroscopic and computational studies

Sourav Das et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2019)

Article Genetics & Heredity

Identification of a novel homozygous variant confirms ITPA as a developmental and epileptic encephalopathy gene

Parneet Kaur et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2019)

Article Chemistry, Medicinal

PlayMolecule ProteinPrepare: A Web Application for Protein Preparation for Molecular Dynamics Simulations

Gerard Martinez-Rosell et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2017)

Article Biochemical Research Methods

Effect of mutation on A beta(1-42)-Heme complex in aggregation mechanism: Alzheimer's disease

Subramaniam Boopathi et al.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2017)

Review Cell Biology

A disease spectrum for ITPA variation: advances in biochemical and clinical research

Nicholas E. Burgis

JOURNAL OF BIOMEDICAL SCIENCE (2016)

Article Clinical Neurology

Recessive ITPA Mutations Cause an Early Infantile Encephalopathy

Sietske H. Kevelam et al.

ANNALS OF NEUROLOGY (2015)

Editorial Material Pharmacology & Pharmacy

The importance of employing computational resources for the automation of drug discovery

Martha Cecilia Rosales-Hernandez et al.

EXPERT OPINION ON DRUG DISCOVERY (2015)

Article Biochemistry & Molecular Biology

Analysis of human ITPase nucleobase specificity by site-directed mutagenesis

Amanda D. Gall et al.

BIOCHIMIE (2013)

Article Biochemistry & Molecular Biology

The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core

Peter D. Simone et al.

JOURNAL OF STRUCTURAL BIOLOGY (2013)

Article Multidisciplinary Sciences

Defects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNA

Bo Pang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Biology

Molecular dynamics simulations and drug discovery

Jacob D. Durrant et al.

BMC BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Quantitative in vitro and in vivo characterization of the human P32T mutant ITPase

Greg Herting et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)

Article Multidisciplinary Sciences

ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C

Jacques Fellay et al.

NATURE (2010)

Article Biochemistry & Molecular Biology

Functional Study of the P32T ITPA Variant Associated with Drug Sensitivity in Humans

Elena I. Stepchenkova et al.

JOURNAL OF MOLECULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Effects of CMAP and electrostatic cutoffs on the dynamics of an integral membrane protein: The phospholamban study

Yao Houndonougbo et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2008)

Article Chemistry, Physical

P-LINCS: A parallel linear constraint solver for molecular simulation

Berk Hess

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2008)

Article Biochemistry & Molecular Biology

Substrate specificity of RdgB protein, a deoxyribonucleoside triphosphate pyrophosphohydrolase

Nicholas E. Burgis et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Pharmacology & Pharmacy

Pharmacogenetic significance of inosine triphosphatase

Jorgen Bierau et al.

PHARMACOGENOMICS (2007)

Article Biochemical Research Methods

Structure of the orthorhombic form of human inosine triphosphate pyrophosphatase

Jason Porta et al.

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2006)

Article Biochemical Research Methods

MultiSeq: unifying sequence and structure data for evolutionary analysis

Elijah Roberts et al.

BMC BIOINFORMATICS (2006)

Review Biochemistry & Molecular Biology

House cleaning, a part of good housekeeping

MY Galperin et al.

MOLECULAR MICROBIOLOGY (2006)

Review Chemistry, Multidisciplinary

GROMACS: Fast, flexible, and free

D Van der Spoel et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Structure and dynamics of phospholamban in solution and in membrane bilayer: Computer simulations

Y Houndonougbo et al.

BIOCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Mutation in the ITPA gene predicts intolerance to azathioprine

AM Marinaki et al.

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2004)

Article Biochemistry & Molecular Biology

Identification of the dITP- and XTP-hydrolyzing protein from Escherichia coli

JH Chung et al.

JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Molecular dynamics Simulations of conformational Behavior of linear RGD peptidomimetics and cyclic Prodrugs in aqueous and octane solutions

J Mahadevan et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2002)

Article Biochemistry & Molecular Biology

Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the ITPA gene

SR Lin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)