4.5 Article

Subdiffuse scattering model for single fiber reflectance spectroscopy

期刊

JOURNAL OF BIOMEDICAL OPTICS
卷 25, 期 1, 页码 -

出版社

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.JBO.25.1.015001

关键词

subdiffuse scattering; backscattering; reflectance spectroscopy; optical properties; single fiber reflectance spectroscopy

资金

  1. Netherlands Organization for Scientific Research (Technology Foundation STW) [12707]
  2. Dutch Cancer Society/Alpe d'HuZes [2014-7009]

向作者/读者索取更多资源

To detect small-scale changes in tissue with optical techniques, small sampling volumes are required. Single fiber reflectance (SFR) spectroscopy has a sampling depth of a few hundred micrometers. SFR spectroscopy uses a single fiber to emit and collect light. The only available model to determine optical properties with SFR spectroscopy was derived for tissues with modified Henyey-Greenstein phase functions. Previously, we demonstrated that this model is inadequate for other tissue phase functions. We develop a model to relate SFR measurements to scattering properties for a range of phase functions, in the absence of absorption. Since the source and detector overlap, the reflectance cannot be accurately described by diffusion theory alone: SFR measurements are subdiffuse. Therefore, we describe the reflectance as a combination of a diffuse and a semiballistic component. We use the model of Farrell et al. for the diffuse component, solved for an overlapping source and detector fiber. For the semiballistic component, we derive a new parameter, p(sb), which incorporates the integrals of the phase function over 1 deg in the backward direction and 23 deg in the forward direction. Our model predicts the reflectance with a median error of 2.1%, compared to 9.0% for the currently available model. (C) The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.5
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据