相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Mechanism of gating and partial agonist action in the glycine receptor
Jie Yu et al.
CELL (2021)
Triple arginines as molecular determinants for pentameric assembly of the intracellular domain of 5-HT3A receptors
Akash Pandhare et al.
JOURNAL OF GENERAL PHYSIOLOGY (2019)
Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer
Duncan Laverty et al.
NATURE (2019)
GABAA receptor signalling mechanisms revealed by structural pharmacology
Simonas Masiulis et al.
NATURE (2019)
Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors
Cesar O. Lara et al.
ACS CHEMICAL NEUROSCIENCE (2019)
Cross-Linking-Mass Spectrometry Studies of Cholesterol Interactions with Human alpha 1 Glycine Receptor
Nicholas A. Ferraro et al.
ANALYTICAL CHEMISTRY (2018)
Cryo-EM structure of 5-HT3A receptor in its resting conformation
Sandip Basak et al.
NATURE COMMUNICATIONS (2018)
PKA and PKC Modulators Affect Ion Channel Function and Internalization of Recombinant Alpha1 and Alpha1-Beta Glycine Receptors
Ulrike Breitinger et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3A receptor
Sandip Basak et al.
NATURE (2018)
Conformational transitions of the serotonin 5-HT3 receptor
Lucie Polovinkin et al.
NATURE (2018)
A tale of ligands big and small: An update on how pentameric ligand-gated ion channels interact with agonists and proteins
Stephan A. Pless et al.
CURRENT OPINION IN PHYSIOLOGY (2018)
Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators
Xin Huang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators
Xin Huang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
The role of charged residues in independent glycine receptor folding domains for intermolecular interactions and ion channel function
Georg Langlhofer et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Pentameric quaternary structure of the intracellular domain of serotonin type 3A receptors
Akash Pandhare et al.
SCIENTIFIC REPORTS (2016)
The Intracellular Loop of the Glycine Receptor: It's not all about the Size
Georg Langlhofer et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2016)
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
Xin Huang et al.
NATURE (2015)
Glycine receptor mechanism elucidated by electron cryo-microscopy
Juan Du et al.
NATURE (2015)
The Role of Intracellular Linkers in Gating and Desensitization of Human Pentameric Ligand-Gated Ion Channels
David Papke et al.
JOURNAL OF NEUROSCIENCE (2014)
X-ray structure of the mouse serotonin 5-HT3 receptor
Gherici Hassaine et al.
NATURE (2014)
Phosphorylation of α3 Glycine Receptors Induces a Conformational Change in the Glycine-Binding Site
Lu Han et al.
ACS CHEMICAL NEUROSCIENCE (2013)
The Minimum M3-M4 Loop Length of Neurotransmitter-activated Pentameric Receptors Is Critical for the Structural Integrity of Cytoplasmic Portals
Daniel T. Baptista-Hon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Nicotinic acetylcholine receptor and the structural basis of neuromuscular transmission: insights from Torpedo postsynapticmembranes
Nigel Unwin
QUARTERLY REVIEWS OF BIOPHYSICS (2013)
A Single Phenylalanine Residue in the Main Intracellular Loop of α1 γ-Aminobutyric Acid Type A and Glycine Receptors Influences Their Sensitivity to Propofol
Gustavo Moraga-Cid et al.
ANESTHESIOLOGY (2011)
Chloride Ions in the Pore of Glycine and GABA Channels Shape the Time Course and Voltage Dependence of Agonist Currents
Mirko Moroni et al.
JOURNAL OF NEUROSCIENCE (2011)
Principles of activation and permeation in an anion-selective Cys-loop receptor
Ryan E. Hibbs et al.
NATURE (2011)
Multifunctional Basic Motif in the Glycine Receptor Intracellular Domain Induces Subunit-specific Sorting
Nima Melzer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Characterization of the Effects of Charged Residues in the Intracellular Loop on Ion Permeation in α1 Glycine Receptor Channels
Jane E. Carland et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The M4 transmembrane segment contributes to agonist efficacy differences between 1 and 3 glycine receptors
Xuebin Chen et al.
MOLECULAR MEMBRANE BIOLOGY (2009)
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
Nicolas Bocquet et al.
NATURE (2009)
Influence of the M3-M4 intracellular domain upon nicotinic acetylcholine receptor assembly, targeting and function
S. Kracun et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Modular design of cys-loop ligand-gated ion channels:: Functional 5-HT3 and GABA ρ1 receptors lacking the large cytoplasmic M3M4 loop
Michaela Jansen et al.
JOURNAL OF GENERAL PHYSIOLOGY (2008)
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
Ricarda J. C. Hilf et al.
NATURE (2008)
On the nature of partial agonism in the nicotinic receptor superfamily
Remigijus Lape et al.
NATURE (2008)
A selective Gβγ-linked intracellular mechanism for modulation of a ligand-gated ion channel by ethanol
Gonzalo E. Yevenes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and α4β2 nicotinic acetylcholine receptors
TG Hales et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Deciphering the structural framework of glycine receptor anchoring by gephyrin
EY Kim et al.
EMBO JOURNAL (2006)
Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution
N Unwin
JOURNAL OF MOLECULAR BIOLOGY (2005)
The activation mechanism of α1 homomeric glycine receptors
M Beato et al.
JOURNAL OF NEUROSCIENCE (2004)
Single-channel behavior of heteromeric α1β glycine receptors:: An attempt to detect a conformational change before the channel opens
V Burzomato et al.
JOURNAL OF NEUROSCIENCE (2004)
Molecular structure and function of the glycine receptor chloride channel
JW Lynch
PHYSIOLOGICAL REVIEWS (2004)
A cytoplasmic region determines single-channel conductance in 5-HT3 receptors
SP Kelley et al.
NATURE (2003)
A basic cluster determines topology of the cytoplasmic M3-M4 loop of the glycine receptor α1 subunit
S Sadtler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Binding site stoichiometry and the effects of phosphorylation on human α1 homomeric glycine receptors
LJ Gentet et al.
JOURNAL OF PHYSIOLOGY-LONDON (2002)
Achieving optimal expression for single channel recording:: a plasmid ratio approach to the expression of α1 glycine receptors in HEK293 cells
PJ Groot-Kormelink et al.
JOURNAL OF NEUROSCIENCE METHODS (2002)
The Croonian Lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission
N Unwin
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2000)