期刊
BRITISH JOURNAL OF NUTRITION
卷 115, 期 7, 页码 1273-1280出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0007114516000040
关键词
Equivalence; Agreement; Dietary assessment; Bland and Altman method
The aim of this study was to demonstrate the use of testing for equivalence in combination with the Bland and Altman method when assessing agreement between two dietary methods. A sample data set, with eighty subjects simulated from previously published studies, was used to compare a FFQ with three 24 h recalls (24HR) for assessing dietary I intake. The mean I intake using the FFQ was 12651 (sd 5406) mu g and using the three 24HR was 12423 (sd 4862) mu g. The bias was -228 (sd 4393) mu g with a 90 % CI 1046, 589 mu g. The limits of agreement (LOA) were -8838, 8382 mu g. Four equivalence regions were compared. Using the conventional 10 % equivalence range, the methods are shown to be equivalent both by using the CI (-124, 124 mu g) and the two one-sided tests approach (lower t=-299 (79 df), P=0002; upper t=206 (79 df), P=0021). However, we make a case that clinical decision making should be used to set the equivalence limits, and for nutrients where there are potential issues with deficiency or toxicity stricter criteria may be needed. If the equivalence region is lowered to +/- 5 mu g, or +/- 10 mu g, these methods are no longer equivalent, and if a wider limit of +/- 15 mu g is accepted they are again equivalent. Using equivalence testing, acceptable agreement must be assessed a priori and justified; this makes the process of defining agreement more transparent and results easier to interpret than relying on the LOA alone.
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