期刊
BRITISH JOURNAL OF NUTRITION
卷 116, 期 4, 页码 728-733出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0007114516002518
关键词
Sodium; Stomach neoplasms; Population attributable fractions; Predictions
资金
- 'Fundo Europeu de Desenvolvi-mento Regional' (FEDER) funds through the 'Programa Operacional Factores de Competitividade' (POFC) - COMPETE [FCOMP-01-0124-FEDER-021181]
- national funds through the 'Fundacao para a Ciencia e a Tecnologia' [PTDC/SAU-EPI/122460/2010]
- Epidemiology Research Unit-Institute of Public Health, University of Porto [UID/DTP/047507/2013]
- Fundação para a Ciência e a Tecnologia [PTDC/SAU-EPI/122460/2010] Funding Source: FCT
Assessing the impact that patterns of Na intake may have on gastric cancer will provide a more comprehensive estimation of Na reduction as a primary prevention approach. We aimed to estimate the proportion of gastric cancer cases that are attributable to Na intake above the recommendation by the WHO (<= 2g/d) throughout the world in 2010, as well as expected values for 2030. Population attributable fractions (PAF) were computed for 187 countries, using Na intakes in 1990 and 2010 and estimates of the association between Na intake and gastric cancer, assuming a time lag of 20 years. Median PAF ranged from 10.1% in low to 22.5% in very high Human Development Index (HDI) countries in men (P < 0.001) and from 7.2 to 16.6%, respectively, among women (P < 0.001). An increase in median PAF until 2030 is expected in most settings, except for countries classified as low HDI, in both sexes. High Na intakes account for a large proportion of gastric cancer cases, and proportions are expected to increase in almost all of the countries. Intensified efforts to diminish Na intake in virtually all populations are needed to further reduce gastric cancer burden.
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