期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 68, 期 2, 页码 574-583出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.9b05649
关键词
polyphenol; bioaccessibility; dynamic gastric model; mucin; cell walls; apple
资金
- Australian Research Council Centre of Excellence in Plant Cell Walls [CE110001007]
- China Scholarship Council
- University of Queensland
Food structure is a key determinant for the release of phenolic compounds during gastric and intestinal digestion. We evaluated the bioaccessibility of polyphenols from apple tissue during gastric digestion in vitro from biomechanical perspectives including the effects of gastric juice and mucin on the apple tissue matrix under simulated stomach peristalsis. The gastric model system was effective in releasing polyphenols because of simultaneous compression and extrusion, with 3 times higher release from coarse than from fine particles. However, bioaccessibility of polyphenols was reduced up to 44% in the presence of both cell walls and gastric mucin. Most individual phenolic molecules were gradually released and were stable in the gastric environment, except for procyanidin B2. The study suggests that the bioaccessibility of polyphenols from apples in the upper digestive tract is dependent on mechanical disintegration and the residual matrix present in the swallowed bolus.
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