Regulation of macrophage-like cell activity driven by atmospheric oxygen plasma

Oxygen plasma that is a kind of external biological stimulus activates the macrophage-like cell. Active oxygen species in the oxygen plasma-irradiated macrophage-like cells in culture medium to investigate the effects of different treatment periods and applied voltages. Macrophage-like cells were activated and increased 10% after 48 h from the short period plasma irradiation of 30 s. The long period irradiation for 60 and 120 s decreased the cell number by almost 33%. The phagocytosis capability increased by 1.5 times during the shorter plasma irradiation period, which would be owing to the increase of active oxygen species inside the macrophage cells. (C) 2020 The Japan Society of Applied Physics.