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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers
Scott P. Delbecq et al.
BIOCHEMISTRY (2015)
Widespread Proteome Remodeling and Aggregation in Aging C-elegans
Dirk M. Walther et al.
CELL (2015)
Phosphomimics Destabilize Hsp27 Oligomeric Assemblies and Enhance Chaperone Activity
Blagojce Jovcevski et al.
CHEMISTRY & BIOLOGY (2015)
HspB8 is Neuroprotective during Oxygen Glucose Deprivation and Reperfusion
Binbin Yang et al.
CURRENT NEUROVASCULAR RESEARCH (2015)
Drosophila small heat shock protein CryAB ensures structural integrity of developing muscles, and proper muscle and heart performance
Inga Wojtowicz et al.
DEVELOPMENT (2015)
Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D
Rocio Bengoechea et al.
HUMAN MOLECULAR GENETICS (2015)
Myofibrillar instability exacerbated by acute exercise in filaminopathy
Frederic Chevessier et al.
HUMAN MOLECULAR GENETICS (2015)
Structure of the α-crystallin domain from the redox-sensitive chaperone, HSPB1
Ponni Rajagopal et al.
JOURNAL OF BIOMOLECULAR NMR (2015)
BAG3-related myopathy, polyneuropathy and cardiomyopathy with long QT syndrome
Anna Kostera-Pruszczyk et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2015)
A novel heat shock protein 27 homozygous mutation: widening of the continuum between MND/dHMN/CMT2
Marina Scarlato et al.
JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM (2015)
Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation
Nadinath B. Nillegoda et al.
NATURE (2015)
The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client
Andi Mainz et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Novel mutations in DNAJB6 gene cause a very severe early-onset limb-girdle muscular dystrophy 1D disease
Johanna Palmio et al.
NEUROMUSCULAR DISORDERS (2015)
A novel mutation in DNAJB6, p.(Phe91Leu), in childhood-onset LGMD1D with a severe phenotype
Tai-Seung Nam et al.
NEUROMUSCULAR DISORDERS (2015)
BAG3 myofibrillar myopathy presenting with cardiomyopathy
Chamindra G. Konersman et al.
NEUROMUSCULAR DISORDERS (2015)
The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client
Andi Mainz et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy
Paola Rusmini et al.
SCIENTIFIC REPORTS (2015)
Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy
Claudia Gonzaga-Jauregui et al.
CELL REPORTS (2015)
A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis
Ponni Rajagopal et al.
ELIFE (2015)
Complete loss of the DNAJB6 G/F domain and novel missense mutations cause distal-onset DNAJB6 myopathy
Alessandra Ruggieri et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Distal hereditary motor neuropathy with HSJ1 chaperone mutation, presenting with peripheral motor neuropathy, associated to parkinsonism, and cerebellar ataxia. Case report
Helio Teive et al.
PARKINSONISM & RELATED DISORDERS (2015)
Desmin in muscle and associated diseases: beyond the structural function
Karim Hnia et al.
CELL AND TISSUE RESEARCH (2015)
Heat Shock Protein 22 (Hsp22) Regulates Oxidative Phosphorylation upon Its Mitochondrial Translocation with the Inducible Nitric Oxide Synthase in Mammalian Heart
Eman Rashed et al.
PLOS ONE (2015)
Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases
Lydia K. Muranova et al.
PLOS ONE (2015)
Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome
Julianne H. Grose et al.
PLOS ONE (2015)
Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain
Jee-Young Mock et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Truncated HSPB1 causes axonal neuropathy and impairs tolerance to unfolded protein stress
Emil Ylikallio et al.
BBA CLINICAL (2015)
Overexpression of mutant HSP27 causes axonal neuropathy in mice
Jinho Lee et al.
JOURNAL OF BIOMEDICAL SCIENCE (2015)
DNAJs: more than substrate delivery to HSPA
Suzanne L. Dekker et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2015)
Zebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency
Avnika A. Ruparelia et al.
ACTA NEUROPATHOLOGICA (2014)
Aggregate-Prone R120GCRYAB Triggers Multifaceted Modifications of the Thioredoxin System
Soumyajit Banerjee Mustafi et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta Implications for a proteasome-to-autophagy switch
Melania Minoia et al.
AUTOPHAGY (2014)
Characterization of human small heat shock protein HspB1 that carries C-terminal domain mutations associated with hereditary motor neuron diseases
Anna S. Chalova et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2014)
A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways
Mikko Taipale et al.
CELL (2014)
DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios
Cecilia Mansson et al.
CELL STRESS & CHAPERONES (2014)
Effect of disulfide crosslinking on thermal transitions and chaperone-like activity of human small heat shock protein HspB1
Anna S. Chalova et al.
CELL STRESS & CHAPERONES (2014)
Congenital posterior pole cataract and adult onset dilating cardiomyopathy: expanding the phenotype of αB-crystallinopathies
J. J. van der Smagt et al.
CLINICAL GENETICS (2014)
Pathology of frontotemporal dementia with limb girdle muscular dystrophy caused by a DNAJB6 mutation
Ichiro Yabe et al.
CLINICAL NEUROLOGY AND NEUROSURGERY (2014)
Contribution of small heat shock proteins to muscle development and function
Magda Dubinska-Magiera et al.
FEBS LETTERS (2014)
Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones
Maria Udan-Johns et al.
HUMAN MOLECULAR GENETICS (2014)
Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro
Jennifer N. Rauch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Myopathy-causing Mutations in an HSP40 Chaperone Disrupt Processing of Specific Client Conformers
Kevin C. Stein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Interaction of the Molecular Chaperone DNAJB6 with Growing Arnyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation
Cecilia Mansson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Crystallin-αB Regulates Skeletal Muscle Homeostasis via Modulation of Argonaute2 Activity
Ronald L. Neppl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins
Sebastian Koetter et al.
JOURNAL OF CELL BIOLOGY (2014)
The BAG3 gene variants in Polish patients with dilated cardiomyopathy: four novel mutations and a genotype-phenotype correlation
Maria Franaszczyk et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2014)
The Functional Landscape of Hsp27 Reveals New Cellular Processes such as DNA Repair and Alternative Splicing and Proposes Novel Anticancer Targets
Maria Katsogiannou et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
DNAJB6 MYOPATHY: A VACUOLAR MYOPATHY WITH CHILDHOOD ONSET
Gerson Suarez-Cedeno et al.
MUSCLE & NERVE (2014)
A novel transgenic mouse model of Chinese Charcot-Marie-Tooth disease type 2L
Ruxu Zhang et al.
NEURAL REGENERATION RESEARCH (2014)
HSJ1-related hereditary neuropathies Novel mutations and extended clinical spectrum
Burkhard Gess et al.
NEUROLOGY (2014)
Exome sequencing identifies a DNAJB6 mutation in a family with dominantly-inherited limb-girdle muscular dystrophy
Julien Couthouis et al.
NEUROMUSCULAR DISORDERS (2014)
Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS
Bradley N. Smith et al.
NEURON (2014)
Unusual multisystemic involvement and a novel BAG3 mutation revealed by NGS screening in a large cohort of myofibrillar myopathies
Anna-Lena Semmler et al.
ORPHANET JOURNAL OF RARE DISEASES (2014)
Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli
Francis Impens et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Cell biological roles of αB-crystallin
Wilbert C. Boelens
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2014)
The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells
Mohamed-Amine Hamouda et al.
ONCOTARGET (2014)
The allelic spectrum of Charcot-Marie-Tooth disease in over 17,000 individuals with neuropathy
Christina DiVincenzo et al.
MOLECULAR GENETICS & GENOMIC MEDICINE (2014)
Chaperoning Proteins for Destruction: Diverse Roles of Hsp70 Chaperones and their Co-Chaperones in Targeting Misfolded Proteins to the Proteasome
Ayala Shiber et al.
BIOMOLECULES (2014)
Charcot-Marie-Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments
Anne Holmgren et al.
ACTA NEUROPATHOLOGICA (2013)
Welander distal myopathy is caused by a mutation in the RNA-binding protein TIA1
Peter Hackman et al.
ANNALS OF NEUROLOGY (2013)
Structure and properties of G84R and L99M mutants of human small heat shock protein HspB1 correlating with motor neuropathy
Victoria V. Nefedova et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2013)
Physico-chemical properties of R140G and K141Q mutants of human small heat shock protein HspB1 associated with hereditary peripheral neuropathies
Victoria V. Nefedova et al.
BIOCHIMIE (2013)
The Small Heat Shock Protein Hsp27 Affects Assembly Dynamics and Structure of Keratin Intermediate Filament Networks
Jona Kayser et al.
BIOPHYSICAL JOURNAL (2013)
Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy
Anna Ulbricht et al.
CURRENT BIOLOGY (2013)
One size does not fit all: The oligomeric states of αB crystallin
Scott P. Delbecq et al.
FEBS LETTERS (2013)
Molecular Mechanisms of Amyloid Oligomers Toxicity
Rakez Kayed et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Structural and Functional Aspects of Hetero-oligomers Formed by the Small Heat Shock Proteins αB-Crystallin and HSP27
J. Andrew Aquilina et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Phenotype of Cardiomyopathy in Cardiac-specific Heat Shock Protein B8 K141N Transgenic Mouse
Atsushi Sanbe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The DNAJB6 and DNAJB8 Protein Chaperones Prevent Intracellular Aggregation of Polyglutamine Peptides
Judith Gillis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
14-3-3 protein targets misfolded chaperone-associated proteins to aggresomes
Zhe Xu et al.
JOURNAL OF CELL SCIENCE (2013)
Enhanced autophagy ameliorates cardiac proteinopathy
Md. Shenuarin Bhuiyan et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Bcl2-associated Athanogene 3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity
Ying Chen et al.
MOLECULAR & CELLULAR PROTEOMICS (2013)
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
Hong Joo Kim et al.
NATURE (2013)
Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress
Stephanie Escusa-Toret et al.
NATURE CELL BIOLOGY (2013)
Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy
Paola Rusmini et al.
NEUROBIOLOGY OF AGING (2013)
DNAJB6 myopathy in an Asian cohort and cytoplasmic/nuclear inclusions
Takatoshi Sato et al.
NEUROMUSCULAR DISORDERS (2013)
A novel Lys141Thr mutation in small heat shock protein 22 (HSPB8) gene in Charcot Marie Tooth disease type 2L
Khriezhanuo Nakhro et al.
NEUROMUSCULAR DISORDERS (2013)
HSPB1 Facilitates the Formation of Non-Centrosomal Microtubules
Leonardo Almeida-Souza et al.
PLOS ONE (2013)
Pseudophosphorylated αB-Crystallin Is a Nuclear Chaperone Imported into the Nucleus with Help of the SMN Complex
John den Engelsman et al.
PLOS ONE (2013)
Analysis of the Dominant Effects Mediated by Wild Type or R120G Mutant of αB-crystallin (HspB5) towards Hsp27 (HspB1)
Stephanie Simon et al.
PLOS ONE (2013)
Molecular Chaperone Mediated Late-Stage Neuroprotection in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
Sergey S. Novoselov et al.
PLOS ONE (2013)
Cell Stress Promotes the Association of Phosphorylated HspB1 with F-Actin
Joseph P. Clarke et al.
PLOS ONE (2013)
The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability
Jayne L. Elliott et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2013)
Regulated structural transitions unleash the chaperone activity of αB-crystallin
Jirka Peschek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Absolute amounts and diffusibility of HSP72, HSP25, and αB-crystallin in fast- and slow-twitch skeletal muscle fibers of rat
Noni T. Larkins et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2012)
A rare recessive distal hereditary motor neuropathy with HSJ1 chaperone mutation
Sergiu C. Blumen et al.
ANNALS OF NEUROLOGY (2012)
Exome sequencing reveals DNAJB6 mutations in dominantly-inherited myopathy
Matthew B. Harms et al.
ANNALS OF NEUROLOGY (2012)
Sequence, Structure, and Dynamic Determinants of Hsp27 (HspB1) Equilibrium Dissociation Are Encoded by the N-Terminal Domain
Ezelle T. McDonald et al.
BIOCHEMISTRY (2012)
Utilization of fluorescent chimeras for investigation of heterooligomeric complexes formed by human small heat shock proteins
Petr N. Datskevich et al.
BIOCHIMIE (2012)
Suppression of protein aggregation by chaperone modification of high molecular weight complexes
John Labbadia et al.
BRAIN (2012)
Structural Aspects and Chaperone Activity of Human HspB3: Role of the C-Terminal Extension
Abhishek Asthana et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2012)
Heterooligomeric complexes of human small heat shock proteins
Evgeny V. Mymrikov et al.
CELL STRESS & CHAPERONES (2012)
BAG3-related myofibrillar myopathy in a Chinese family
H. C. Lee et al.
CLINICAL GENETICS (2012)
The Role of Intrinsically Disordered Regions in the Structure and Functioning of Small Heat Shock Proteins
Maria V. Sudnitsyna et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2012)
Binding determinants of the small heat shock protein, αB-crystallin: recognition of the 'IxI' motif
Scott P. Delbecq et al.
EMBO JOURNAL (2012)
Cellular stress stimulates nuclear localization signal (NLS) independent nuclear transport of MRJ
Joel F. Andrews et al.
EXPERIMENTAL CELL RESEARCH (2012)
Cardiac H11 kinase/Hsp22 stimulates oxidative phosphorylation and modulates mitochondrial reactive oxygen species production: Involvement of a nitric oxide-dependent mechanism
Lydie Laure et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death
Julie Acunzo et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)
Structural and Mechanistic Implications of Metal Binding in the Small Heat-shock Protein αB-crystallin
Andi Mainz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
NF-κB regulates protein quality control after heat stress through modulation of the BAG3-HspB8 complex
Mathieu Nivon et al.
JOURNAL OF CELL SCIENCE (2012)
BAG3 mutations: another cause of giant axonal neuropathy
Fatima Jaffer et al.
JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM (2012)
Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy
Jaakko Sarparanta et al.
NATURE GENETICS (2012)
Mutant HSPB1 overexpression in neurons is sufficient to cause age-related motor neuronopathy in mice
Amit K. Srivastava et al.
NEUROBIOLOGY OF DISEASE (2012)
Mutant HSPB8 causes protein aggregates and a reduced mitochondrial membrane potential in dermal fibroblasts from distal hereditary motor neuropathy patients
Joy Irobi et al.
NEUROMUSCULAR DISORDERS (2012)
A novel CRYAB mutation resulting in multisystemic disease
Sabrina Sacconi et al.
NEUROMUSCULAR DISORDERS (2012)
The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases
K. Seidel et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2012)
DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin
A. Mitra et al.
ONCOGENE (2012)
HspB2/Myotonic Dystrophy Protein Kinase Binding Protein (MKBP) as a Novel Molecular Chaperone: Structural and Functional Aspects
Sankaralingam Prabhu et al.
PLOS ONE (2012)
HSPB2 Is Dispensable for the Cardiac Hypertrophic Response but Reduces Mitochondrial Energetics following Pressure Overload In Mice
Takahiro Ishiwata et al.
PLOS ONE (2012)
Chaperones in autophagy
Susmita Kaushik et al.
PHARMACOLOGICAL RESEARCH (2012)
Genome-wide Studies of Copy Number Variation and Exome Sequencing Identify Rare Variants in BAG3 as a Cause of Dilated Cardiomyopathy
Nadine Norton et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
Preemptive conditioning of the swine heart by H11 kinase/Hsp22 provides cardiac protection through inducible nitric oxide synthase
Li Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
Infantile Muscular Dystrophy in Canadian Aboriginals Is an αB-Crystallinopathy
Marc R. Del Bigio et al.
ANNALS OF NEUROLOGY (2011)
Sustained Activation of Nuclear Erythroid 2-Related Factor 2/Antioxidant Response Element Signaling Promotes Reductive Stress in the Human Mutant Protein Aggregation Cardiomyopathy in Mice
Namakkal Soorappan Rajasekaran et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Biochemical characterization of small heat shock protein HspB8 (Hsp22)-Bag3 interaction
Anton A. Shemetov et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)
The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities
Jurre Hageman et al.
BIOCHEMICAL JOURNAL (2011)
H11 Kinase/Heat Shock Protein 22 Deletion Impairs Both Nuclear and Mitochondrial Functions of STAT3 and Accelerates the Transition Into Heart Failure on Cardiac Overload
Hongyu Qiu et al.
CIRCULATION (2011)
Atg7 Induces Basal Autophagy and Rescues Autophagic Deficiency in CryABR120G Cardiomyocytes
J. Scott Pattison et al.
CIRCULATION RESEARCH (2011)
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins
Martin Gamerdinger et al.
EMBO REPORTS (2011)
A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy
Eric Villard et al.
EUROPEAN HEART JOURNAL (2011)
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
Johanna M. Rose et al.
HUMAN MOLECULAR GENETICS (2011)
Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes
Takuro Arimura et al.
HUMAN MUTATION (2011)
Hsp42 is required for sequestration of protein aggregates into deposition sites in Saccharomyces cerevisiae
Sebastian Specht et al.
JOURNAL OF CELL BIOLOGY (2011)
Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice
Jie Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
The Neurodegenerative-Disease-Related Protein Sacsin Is a Molecular Chaperone
John F. Anderrson et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Crystal Structure of R120G Disease Mutant of Human αB-Crystallin Domain Dimer Shows Closure of a Groove
A. R. Clark et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
HspB8 mutation causing hereditary distal motor neuropathy impairs lysosomal delivery of autophagosomes
Alice S. Kwok et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Small Heat-Shock Protein HSPB1 Mutants Stabilize Microtubules in Charcot-Marie-Tooth Neuropathy
Leonardo Almeida-Souza et al.
JOURNAL OF NEUROSCIENCE (2011)
Map3k1, Il6st, Gzmk, and Hspb3 Gene Coexpression Network in the Mechanism of Freezing Reaction in Mice
Elena M. Kondaurova et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2011)
Differential Expression and Induction of Small Heat Shock Proteins in Rat Brain and Cultured Hippocampal Neurons
Britta Bartelt Kirbach et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2011)
HSPB1 and HSPB8 in inherited neuropathies: study of an Italian cohort of dHMN and CMT2 patients
Simona Capponi et al.
JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM (2011)
Phosphorylation of human small heat shock protein HspB8 (Hsp22) by ERK1 protein kinase
Anton A. Shemetov et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2011)
The Cytosolic Chaperone Hsc70 Promotes Traffic to the Cell Surface of Intracellular Retained Melanocortin-4 Receptor Mutants
Eirini Meimaridou et al.
MOLECULAR ENDOCRINOLOGY (2011)
HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1-induced Charcot-Marie-Tooth disease
Constantin d'Ydewalle et al.
NATURE MEDICINE (2011)
Infantile onset myofibrillar myopathy due to recessive CRYAB mutations
Katharine M. L. Forrest et al.
NEUROMUSCULAR DISORDERS (2011)
A Knock-In Mouse Model for the R120G Mutation of αB-Crystallin Recapitulates Human Hereditary Myopathy and Cataracts
Usha P. Andley et al.
PLOS ONE (2011)
Co-Chaperone HSJ1a Dually Regulates the Proteasomal Degradation of Ataxin-3
Xue-Chao Gao et al.
PLOS ONE (2011)
The Mutational Spectrum in a Cohort of Charcot-Marie-Tooth Disease Type 2 among the Han Chinese in Taiwan
Kon-Ping Lin et al.
PLOS ONE (2011)
N-terminal domain of αB-crystallin provides a conformational switch for multimerization and structural heterogeneity
Stefan Jehle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Inhibition of α-synuclein aggregation by small heat shock proteins
Ilona B. Bruinsma et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2011)
BAG3: a multifaceted protein that regulates major cell pathways
A. Rosati et al.
CELL DEATH & DISEASE (2011)
DNAJB2 Expression in Normal and Diseased Human and Mouse Skeletal Muscle
Kristl G. Claeys et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Identification of the key structural motifs involved in HspB8/HspB6-Bag3 interaction
Margit Fuchs et al.
BIOCHEMICAL JOURNAL (2010)
Why proteins without an α-crystallin domain should not be included in the human small heat shock protein family HSPB
Guido Kappe et al.
CELL STRESS & CHAPERONES (2010)
Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3)
Xiankui Sun et al.
CELL STRESS & CHAPERONES (2010)
BAG3 and Hsc70 Interact With Actin Capping Protein CapZ to Maintain Myofibrillar Integrity Under Mechanical Stress
Akinori Hishiya et al.
CIRCULATION RESEARCH (2010)
Manipulation of Death Pathways in Desmin-Related Cardiomyopathy
Alina Maloyan et al.
CIRCULATION RESEARCH (2010)
Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance
Verena Arndt et al.
CURRENT BIOLOGY (2010)
Dynamic processes that reflect anti-apoptotic strategies set up by HspB1 (Hsp27)
Catherine Paul et al.
EXPERIMENTAL CELL RESEARCH (2010)
Independent evolution of the core domain and its flanking sequences in small heat shock proteins
Thomas Kriehuber et al.
FASEB JOURNAL (2010)
Mutant HSPB8 causes motor neuron-specific neurite degeneration
Joy Irobi et al.
HUMAN MOLECULAR GENETICS (2010)
HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones
Michel J. Vos et al.
HUMAN MOLECULAR GENETICS (2010)
The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)
Valeria Crippa et al.
HUMAN MOLECULAR GENETICS (2010)
Involvement of Reductive Stress in the Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Heat Shock Protein 27
Xia Zhang et al.
HYPERTENSION (2010)
Increased Monomerization of Mutant HSPB1 Leads to Protein Hyperactivity in Charcot-Marie-Tooth Neuropathy
Leonardo Almeida-Souza et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
DNAJB6 Induces Degradation of β-Catenin and Causes Partial Reversal of Mesenchymal Phenotype
Aparna Mitra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Identification of the Drosophila Ortholog of HSPB8 IMPLICATION OF HSPB8 LOSS OF FUNCTION IN PROTEIN FOLDING DISEASES
Serena Carra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Role of DnaJ G/F-rich Domain in Conformational Recognition and Binding of Protein Substrates
Judit Perales-Calvo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
BAG-6 is essential for selective elimination of defective proteasomal substrates
Ryosuke Minami et al.
JOURNAL OF CELL BIOLOGY (2010)
Characterization of BAG3 Cleavage During Apoptosis of Pancreatic Cancer Cells
Hua-Qin Wang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathways
Huali Zhang et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
Doxycycline Attenuates Protein Aggregation in Cardiomyocytes and Improves Survival of a Mouse Model of Cardiac Proteinopathy
Hanqiao Zheng et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)
A novel HSPB1 mutation in an Italian patient with CMT2/dHMN phenotype
M. Luigetti et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2010)
A DNAJB Chaperone Subfamily with HDAC-Dependent Activities Suppresses Toxic Protein Aggregation
Jurre Hageman et al.
MOLECULAR CELL (2010)
`The HSP70 chaperone machinery: J proteins as drivers of functional specificity
Harm H. Kampinga et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Mutant small heat shock protein B3 causes motor neuropathy Utility of a candidate gene approach
S. J. Kolb et al.
NEUROLOGY (2010)
The p.G154S mutation of the alpha-B crystallin gene (CRYAB) causes late-onset distal myopathy
Peter Reilich et al.
NEUROMUSCULAR DISORDERS (2010)
Inheritance patterns and phenotypic features of myofibrillar myopathy associated with a BAG3 mutation
Zagaa Odgerel et al.
NEUROMUSCULAR DISORDERS (2010)
Dynamic Subunit Exchange and the Regulation of Microtubule Assembly by the Stress Response Protein Human αB Crystallin
Scott A. Houck et al.
PLOS ONE (2010)
Peripheral Protein Quality Control Removes Unfolded CFTR from the Plasma Membrane
Tsukasa Okiyoneda et al.
SCIENCE (2010)
Differential involvement of sarcomeric proteins in myofibrillar myopathies: a morphological and immunohistochemical study
Kristl G. Claeys et al.
ACTA NEUROPATHOLOGICA (2009)
Mutation in BAG3 Causes Severe Dominant Childhood Muscular Dystrophy
Duygu Selcen et al.
ANNALS OF NEUROLOGY (2009)
Abnormal Assemblies and Subunit Exchange of αB-Crystallin R120 Mutants Could Be Associated with Destabilization of the Dimeric Substructure
Magalie Michiel et al.
BIOCHEMISTRY (2009)
Thermally induced structural changes of intrinsically disordered small heat shock protein Hsp22
Alexey S. Kazakov et al.
BIOPHYSICAL CHEMISTRY (2009)
Myofibrillar Myopathies: A Clinical and Myopathological Guide
Rolf Schroeder et al.
BRAIN PATHOLOGY (2009)
Guidelines for the nomenclature of the human heat shock proteins
Harm H. Kampinga et al.
CELL STRESS & CHAPERONES (2009)
Biochemical and Mechanical Dysfunction in a Mouse Model of Desmin-Related Myopathy
Alina Maloyan et al.
CIRCULATION RESEARCH (2009)
Neural Stem Cell Self-renewal Requires the Mrj Co-chaperone
Erica D. Watson et al.
DEVELOPMENTAL DYNAMICS (2009)
Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
Martin Gamerdinger et al.
EMBO JOURNAL (2009)
The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1
David A. Parfitt et al.
HUMAN MOLECULAR GENETICS (2009)
HspB8 Participates in Protein Quality Control by a Non-chaperone-like Mechanism That Requires eIF2α Phosphorylation
Serena Carra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Single Molecule Force Spectroscopy of the Cardiac Titin N2B Element EFFECTS OF THE MOLECULAR CHAPERONE αB-CRYSTALLIN WITH DISEASE-CAUSING MUTATIONS
Yi Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Phosphorylation Dependence of Hsp27 Multimeric Size and Molecular Chaperone Function
David Hayes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Autoregulation of Co-Chaperone BAG3 Gene Transcription
Antonio Gentilella et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
Proteasome Inhibitor MG132 Induces BAG3 Expression Through Activation of Heat Shock Factor 1
Zhen-Xian Du et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
The Small Heat-Shock Proteins HSPB2 and HSPB3 Form Well-defined Heterooligomers in a Unique 3 to 1 Subunit Ratio
John den Engelsman et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Crystal Structures of α-Crystallin Domain Dimers of αB-Crystallin and Hsp20
C. Bagneris et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Novel Subtype-Specific Genes Identify Distinct Subpopulations of Callosal Projection Neurons
Bradley J. Molyneaux et al.
JOURNAL OF NEUROSCIENCE (2009)
A clinical phenotype of distal hereditary motor neuronopathy type II with a novel HSPB1 mutation
Yoshihisa Ikeda et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2009)
Substrate binding site flexibility of the small heat shock protein molecular chaperones
Nomalie Jaya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus
Dong-Ye Youn et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Gene expression profiling in human skeletal muscle during recovery from eccentric exercise
D. J. Mahoney et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2008)
HspB8 and Bag3 - A new chaperone complex targeting misfolded proteins to macroautophagy
Serena Carra et al.
AUTOPHAGY (2008)
The Hsp40 family chaperone protein DnaJB6 enhances Schlafen1 nuclear localization which is critical for promotion of cell-cycle arrest in T-cells
Yafeng Zhang et al.
BIOCHEMICAL JOURNAL (2008)
Phosphorylation by cyclic AMP-dependent protein kinase inhibits chaperone-like activity of human HSP22 in vitro
A. A. Shemetov et al.
BIOCHEMISTRY-MOSCOW (2008)
Truncation of αB-crystallin by the myopathy-causing Q151X mutation significantly destabilizes the protein leading to aggregate formation in transfected cells
Victoria H. Hayes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Small heat shock protein activity is regulated by variable oligomeric substructure
Justin L. P. Benesch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
bag3 gene expression is regulated by heat shock factor 1
Silvia Franceschelli et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Non-pathogenic protein aggregates in skeletal muscle in MLF1 transgenic mice
Zhi-Fang Li et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)
Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2
H. Houlden et al.
NEUROLOGY (2008)
Electron microscopy in myofibrillar myopathies reveals clues to the mutated gene
K. G. Claeys et al.
NEUROMUSCULAR DISORDERS (2008)
Global expression profiling identifies a novel biosignature for protein aggregation R120GCryAB cardiomyopathy in mice
Namakkal S. Rajasekaran et al.
PHYSIOLOGICAL GENOMICS (2008)
Autophagy is an adaptive response in desmin-related cardiomyopathy
Paul Tannous et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Impaired placental trophoblast lineage differentiation in Alkbh1-/- mice
Zishu Pan et al.
DEVELOPMENTAL DYNAMICS (2008)
Proteasome activation during cardiac hypertrophy by the chaperone H11 Kinase/Hsp22
Nadia Hedhli et al.
CARDIOVASCULAR RESEARCH (2008)
HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy
Serena Carra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Glycogen synthase kinase 3β suppresses myogenic differentiation through negative regulation of NFATc3
Jos L. J. van der Velden et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer
Aparna Mitra et al.
BREAST CANCER RESEARCH (2008)
Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1
Jinbin Zhai et al.
HUMAN MOLECULAR GENETICS (2007)
Myopathy-associated αB-crystallin mutants -: Abnormal phosphorylation, intracellular location, and interactions with other small heat shock proteins
Stephanie Simon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Absence of keratin 19 in mice causes skeletal myopathy with mitochondrial and sarcolemmal reorganization
Michele R. StoneO et al.
JOURNAL OF CELL SCIENCE (2007)
CRYAB and HSPB2 deficiency alters cardiac metabolism and paradoxically confers protection against myocardial ischemia in aging mice
Ivor J. Benjamin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Small heat shock protein Hsp27 prevents heat-induced aggregation of F-actin by forming soluble complexes with denatured actin
Anastasia V. Pivovarova et al.
FEBS JOURNAL (2007)
Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human αA-, αβ- and R120G αB-Crystallins
Sarah Meehan et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Residue R120 is essential for the quaternary structure and functional integrity of human αB-Crystallin
Stephanie Simon et al.
BIOCHEMISTRY (2007)
Human αB-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice
Namakkal S. Rajasekaran et al.
CELL (2007)
Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption
Lei Huang et al.
GENESIS (2007)
Genetic Variant in the HSPB1 Promoter Region Impairs the HSP27 Stress Response
Ines Dierick et al.
HUMAN MUTATION (2007)
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
Udai Bhan Pandey et al.
NATURE (2007)
Interactive Domains in the Molecular Chaperone Human αB Crystallin Modulate Microtubule Assembly and Disassembly
Joy G. Ghosh et al.
PLOS ONE (2007)
Hsp40 molecules that target to the ubiquitin-proteasome system decrease inclusion formation in models of polyglutamine disease
J. L. Howarth et al.
MOLECULAR THERAPY (2007)
The Mrj co-chaperone mediates keratin turnover and prevents the formation of toxic inclusion bodies in trophoblast cells of the placenta
Erica D. Watson et al.
DEVELOPMENT (2007)
Exercise reverses preamyloid oligomer and prolongs survival in αB-crystallin-based desmin-related cardiomyopathy
Alina Maloyan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein
Sovan Sarkar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Interruption of CryAB-Amyloid oligomer formation by HSP22
Atsushi Sanbe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mimicking phosphorylation of alpha B-crystallin affects its chaperone activity
Heath Ecroyd et al.
BIOCHEMICAL JOURNAL (2007)
Apoptosis inhibition in cancer cells: A novel molecular pathway that involves BAG3 protein
Alessandra Rosati et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
Interactive sequences in the stress protein and molecular chaperone human alpha B crystallin recognize and modulate the assembly of filaments
Joy G. Ghosh et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
The N-terminal arm of small heat shock proteins is important for both chaperone activity and substrate specificity
Eman Basha et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A Drosophila ortholog of the human MRJ modulates polyglutamine toxicity and aggregation
Zahra Fayazi et al.
NEUROBIOLOGY OF DISEASE (2006)
Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone
Douglas R. Hurst et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Structure and properties of K141E mutant of small heat shock protein HSP22 (HspB8, H11) that is expressed in human neuromuscular disorders
Maria V. Kim et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2006)
Abnormal small heat shock protein interactions involving neuropathy-associated HSP22 (HSPB8) mutants
Jean-Marc Fontaine et al.
FASEB JOURNAL (2006)
BAG3 deficiency results in fulminant myopathy and early lethality
Sachiko Homma et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
αB-Crystallin mutation in dilated cardiomyopathies:: Low prevalence in a consecutive series of 200 unrelated probands
Andrea Pilotto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
CRYAB and HSPB2 deficiency increases myocyte mitochondrial permeability transition and mitochondrial calcium uptake
Toshie Kadono et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2006)
The role of the DIF motif of the DnaJ (Hsp40) co-chaperone in the regulation of the DnaK (Hsp70) chaperone cycle
GC Cajo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase
M Borrell-Pagès et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Alpha-crystallin expression affects microtubule assembly and prevents their aggregation
Jing-Hua Xi et al.
FASEB JOURNAL (2006)
αB-crystallin mutation in dilated cardiomyopathy
N Inagaki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
A novel αB-crystallin mutation associated with autosomal dominant congenital lamellar cataract
YZ Liu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
H11 kinase prevents myocardial infarction by preemptive preconditioning of the heart
C Depre et al.
CIRCULATION RESEARCH (2006)
A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes
S Ackerley et al.
HUMAN MOLECULAR GENETICS (2006)
Trehalose reduces aggregate formation and delays pathology in a transgenic mouse model of oculopharyngeal muscular dystrophy
JE Davies et al.
HUMAN MOLECULAR GENETICS (2006)
Ischemia-induced increase of stiffness of alpha B-crystallin/HSPB2-deficient myocardium
N Golenhofen et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2006)
Heat shock protein 27 downregulates the transferrin receptor 1-mediated iron uptake
Huaiyong Chen et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2006)
Mitochondrial dysfunction and apoptosis underlie the pathogenic process in α-β-crystallin desmin-related cardiomyopathy
A Maloyan et al.
CIRCULATION (2005)
Interactions of HSP22 (HSPB8) with HSP20, αB-crystallin, and HSPB3
JM Fontaine et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Intrasarcoplasmic amyloidosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake
QH Chen et al.
CIRCULATION RESEARCH (2005)
Nuclear import of αB-crystallin is phosphorylation-dependent and hampered by hyperphosphorylation of the myopathy-related mutant R120G
J den Englesman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment
YS Dai et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy
A Sanbe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Small heat shock protein 27 mutation in a Japanese patient with distal hereditary motor neuropathy
K Kijima et al.
JOURNAL OF HUMAN GENETICS (2005)
Evidence for sequestration of polyglutamine inclusions by Drosophila myeloid leukemia factor
WY Kim et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2005)
The activation mechanism of Hsp26 does not require dissociation of the oligomer
TM Franzmann et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
A chaperone pathway in protein disaggregation - Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104
AG Cashikar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells
S Carra et al.
HUMAN MOLECULAR GENETICS (2005)
HSJ1 is a neuronal shuttling factor for the sorting of chaperone clients to the proteasome
B Westhoff et al.
CURRENT BIOLOGY (2005)
Hsp27 consolidates intracellular redox homeostasis by upholding glutathione in its reduced form and by decreasing iron intracellular levels
AP Arrigo et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Substitution of the unique cysteine residue of murine Hsp25 interferes with the protective activity of this stress protein through inhibition of dimer formation
C Diaz-Latoud et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Mechanism of chaperone function in small heat shock proteins - Dissociation of the Hsp27 oligomer is required for recognition and binding of destabilized T4 lysozyme
R Shashidharamurthy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
R120G αB-crystallin promotes the unfolding of reduced α-lactalbumin and is inherently unstable
TM Treweek et al.
FEBS JOURNAL (2005)
Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L
BS Tang et al.
HUMAN GENETICS (2005)
Remodelling of the nuclear lamina and nucleoskeleton is required for skeletal muscle differentiation in vitro
E Markiewicz et al.
JOURNAL OF CELL SCIENCE (2005)
Roles for αB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model
LE Morrison et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractions
TJ Koh et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Association of the chaperone αB-crystallin with titin in heart muscle
B Bullard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Distribution of proline-rich (PxxP) motifs in distinct proteomes: functional and therapeutic implications for malaria and tuberculosis
BR Chandra et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2004)
Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation
S Meehan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Interaction of human HSP22 (HSPB8) with other small heat shock proteins
XK Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Heat stress-induced localization of small heat shock proteins in mouse myoblasts:: intranuclear lamin A/C speckles as target for αB-crystallin and Hsp25
AS Adhikari et al.
EXPERIMENTAL CELL RESEARCH (2004)
Mammalian Hsp22 is a heat-inducible small heat-shock protein with chaperone-like activity
TK Chowdary et al.
BIOCHEMICAL JOURNAL (2004)
Desmin-related cardiomyopathy in transgenic mice: A cardiac amyloidosis
A Sanbe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Comparison of the small heat shock proteins αB-crystallin, MKBP, HSP25, HSP20, and cvHSP in heart and skeletal muscle
N Golenhofen et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2004)
HSP25 protects skeletal muscle cells against oxidative stress
J Escobedo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Mimicking phosphorylation of the small heat-shock protein αB-crystallin recruits the F-box protein FBX4 to nuclear SC35 speckles
J den Engelsman et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy
J Irobi et al.
NATURE GENETICS (2004)
Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy
OV Evgrafov et al.
NATURE GENETICS (2004)
Desmin aggregate formation by R120G αB-crystallin is caused by altered filament interactions and is dependent upon network status in cells
MD Perng et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
Y Kawaguchi et al.
CELL (2003)
αB-crystallin modulates protein aggregation of abnormal desmin
XJ Wang et al.
CIRCULATION RESEARCH (2003)
Polydispersity of a mammalian chaperone:: Mass spectrometry reveals the population of oligomers in αB-crystallin
JA Aquilina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Characterization of two isoforms of a human DnaJ homologue, HSJ2
R Hanai et al.
MOLECULAR BIOLOGY REPORTS (2003)
Refolding of substrates bound to small Hsps relies on a disaggregation reaction mediated most efficiently by ClpB/DnaK
A Mogk et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
HSP27 is a ubiquitin-binding protein involved in I-κBα proteasomal degradation
A Parcellier et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation - Accumulation of poly-ubiquitinated Hsp90 client proteins
H Doong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Nuclear speckle localisation of the small heat shock protein αB-crystallin and its inhibition by the R120G cardiomyopathy-linked mutation
P van den IJssel et al.
EXPERIMENTAL CELL RESEARCH (2003)
Distinct chaperone mechanisms can delay the formation of aggresomes by the myopathy-causing R120G αB-crystallin mutant
ATC Zobel et al.
HUMAN MOLECULAR GENETICS (2003)
Hsp27 suppresses the formation of inclusion bodies induced by expression of R120GαB-crystallin, a cause of desmin-related myopathy
H Ito et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2003)
The chaperone environment at the cytoplasmic face of the endoplasmic reticulum can modulate rhodopsin processing and inclusion formation
JP Chapple et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mechanism of chaperone function in small heat-shock proteins -: Phosphorylation-induced activation of two-mode binding in αB-crystallin
HA Koteiche et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis
F Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations
D Selcen et al.
ANNALS OF NEUROLOGY (2003)
Changes in oligomerization are essential for the chaperone activity of a small heat shock protein in vivo and in vitro
KC Giese et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The small heat shock protein αB-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation
MC Kamradt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
S-thiolation of HSP27 regulates its multimeric aggregate size independently of phosphorylation
P Eaton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Characterization of a brain-enriched chaperone, MRJ, that inhibits huntingtin aggregation and toxicity independently
JZ Chuang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Translocation of small heat shock proteins to the actin cytoskeleton upon proteasomal inhibition
P Verschuure et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2002)
Ischemia-induced association of the stress protein alpha B-crystallin with I-band portion of cardiac titin
N Golenhofen et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2002)
Association of HSPB2, a member of the small heat shock protein family, with mitochondria
M Nakagawa et al.
EXPERIMENTAL CELL RESEARCH (2001)
Molecular chaperone targeting and regulation by BAG family proteins
S Takayama et al.
NATURE CELL BIOLOGY (2001)
Characterization of two novel human small heat shock proteins:: protein kinase-related HspB8 and testis-specific HspB9
G Kappé et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2001)
HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 (3DHSP27)
R Benndorf et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Expression of R120G-αB-crystallin causes aberrant desmin and αB-crystallin aggregation and cardiomyopathy in mice
XJ Wang et al.
CIRCULATION RESEARCH (2001)
Identification of Mrj, a DnaJ/Hsp40 family protein, as a keratin 8/18 filament regulatory protein
I Izawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The small heat shock protein Hsp22 of Drosophila melanogaster is a mitochondrial protein displaying oligomeric organization
G Morrow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Inhibition of Daxx-mediated apoptosis by heat shock protein 27
SJ Charette et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Desmin cytoskeleton linked to muscle mitochondrial distribution and respiratory function
DJ Milner et al.
JOURNAL OF CELL BIOLOGY (2000)
Hsp27 negatively regulates cell death by interacting with cytochrome c
JM Bruey et al.
NATURE CELL BIOLOGY (2000)
Interaction of the human DnaJ homologue, HSJ1b with the 90 kDa heat shock protein, Hsp90
T Schnaider et al.
LIFE SCIENCES (2000)
ARSACS, a spastic ataxia common in northeastern Quebec, is caused by mutations in a new gene encoding an 11.5-kb ORF
JC Engert et al.
NATURE GENETICS (2000)
Subunit exchange of small heat shock proteins -: Analysis of oligomer formation of αA-crystallin and Hsp27 by fluorescence resonance energy transfer and site-directed truncations
MP Bova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation
Y Sugiyama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
A small heat shock protein cooperates with heat shock protein 70 systems to reactivate a heat-denatured protein
GJ Lee et al.
PLANT PHYSIOLOGY (2000)
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