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Veronica Cartocci et al.
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Vidhi Gaur et al.
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Cong-Hui Yao et al.
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Valeria Pesiri et al.
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Zuzana Papackova et al.
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Hongjin Lu et al.
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Steve Meaney
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J.T. Rocha et al.
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Salih J. Wakil et al.
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D Eberlé et al.
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KM Wojtanik et al.
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