4.7 Article

Inhibition of Bromodomain and Extraterminal Domain (BET) Proteins by JQ1 Unravels a Novel Epigenetic Modulation to Control Lipid Homeostasis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biotechnology & Applied Microbiology

Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation

Carmel J. W. Stock et al.

BIOMED RESEARCH INTERNATIONAL (2019)

Review Biochemistry & Molecular Biology

Loss of Mevalonate/Cholesterol Homeostasis in the Brain: A Focus on Autism Spectrum Disorder and Rett Syndrome

Marco Segatto et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Biochemistry & Molecular Biology

The Hippo pathway modulates resistance to BET proteins inhibitors in lung cancer cells

Giulia Gobbi et al.

ONCOGENE (2019)

Article Endocrinology & Metabolism

Lipid and glucose metabolism in hepatocyte cell lines and primary mouse hepatocytes: a comprehensive resource for in vitro studies of hepatic metabolism

Shilpa R. Nagarajan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2019)

Review Oncology

BET Proteins as Targets for Anticancer Treatment

Anastasios Stathis et al.

CANCER DISCOVERY (2018)

Review Physiology

SR-B1: A Unique Multifunctional Receptor for Cholesterol Influx and Efflux

Wen-Jun Shen et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 80 (2018)

Article Integrative & Complementary Medicine

Synergistic effect of phytochemicals on cholesterol metabolism and lipid accumulation in HepG2 cells

Ennian Leng et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2018)

Review Cell Biology

BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment

Guillaume P. Andrieu et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

Jun-ichi Sakamaki et al.

MOLECULAR CELL (2017)

Article Multidisciplinary Sciences

Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival

Marco Segatto et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis

Thomas C. Roberts et al.

SCIENTIFIC REPORTS (2017)

Article Biochemistry & Molecular Biology

Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells

Darius Ebrahimi-Fakhari et al.

HUMAN MOLECULAR GENETICS (2016)

Article Biochemistry & Molecular Biology

Modulation of the Isoprenoid/Cholesterol Biosynthetic Pathway During Neuronal Differentiation In Vitro

Veronica Cartocci et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2016)

Article Biochemistry & Molecular Biology

Exogenous Fatty Acids Are the Preferred Source of Membrane Lipids in Proliferating Fibroblasts

Cong-Hui Yao et al.

CELL CHEMICAL BIOLOGY (2016)

Review Biochemistry & Molecular Biology

Fatty Acid Signaling: The New Function of Intracellular Lipases

Zuzana Papackova et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Review Biochemistry & Molecular Biology

Beating the odds: BETs in disease

Chen-Yi Wang et al.

TRENDS IN BIOCHEMICAL SCIENCES (2015)

Review Biochemistry & Molecular Biology

The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition

Junwei Shi et al.

MOLECULAR CELL (2014)

Review Genetics & Heredity

Epigenetic regulation of cholesterol homeostasis

Steve Meaney

FRONTIERS IN GENETICS (2014)

Article Biochemistry & Molecular Biology

Molecular Effects of Diphenyl Diselenide on Cholesterol and Glucose Cell Metabolism

J.T. Rocha et al.

CURRENT MEDICINAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

Scavenger receptor-BI is a receptor for lipoprotein(a)

Xiao-Ping Yang et al.

JOURNAL OF LIPID RESEARCH (2013)

Article Biochemical Research Methods

Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease

Annika Mehlem et al.

NATURE PROTOCOLS (2013)

Article Biochemistry & Molecular Biology

Linking epigenetics to lipid metabolism: Focus on histone deacetylases

Alessandra Ferrari et al.

MOLECULAR MEMBRANE BIOLOGY (2012)

Article Multidisciplinary Sciences

Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts

Nina H. Pipalia et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Cell Biology

Lysosomal Lipid Storage Diseases

Heike Schulze et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)

Review Biochemistry & Molecular Biology

Defective cholesterol trafficking in Niemann-Pick C-deficient cells

Kyle B. Peake et al.

FEBS LETTERS (2010)

Article Biochemistry & Molecular Biology

Sterol Regulatory Element-binding Protein (SREBP)-1-mediated Lipogenesis Is Involved in Cell Senescence

You-Mie Kim et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Multidisciplinary Sciences

Selective inhibition of BET bromodomains

Panagis Filippakopoulos et al.

NATURE (2010)

Review Cell Biology

Coordination of Lipid Metabolism in Membrane Biogenesis

Axel Nohturfft et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2009)

Article Cell Biology

Identification of Cholesterol-Regulating Genes by Targeted RNAi Screening

Fabian Bartz et al.

CELL METABOLISM (2009)

Article Biochemistry & Molecular Biology

Fatty acid metabolism: target for metabolic syndrome

Salih J. Wakil et al.

JOURNAL OF LIPID RESEARCH (2009)

Article Neurosciences

Glia-induced neuronal differentiation by transcriptional regulation

Christian Goritz et al.

Review Biochemistry & Molecular Biology

Lipid-lowering drugs

K. Pahan

CELLULAR AND MOLECULAR LIFE SCIENCES (2006)

Review Biochemistry & Molecular Biology

SREBP transcription factors:: master regulators of lipid homeostasis

D Eberlé et al.

BIOCHIMIE (2004)

Article Biochemistry & Molecular Biology

The transport of low density lipoprotein-derived cholesterol to the plasma membrane is defective in NPC1 cells

KM Wojtanik et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)