相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Nonlinearities in the cellular response to ionizing radiation and the role of p53 therein
David Murray et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2021)
Apoptotic cell-derived exosomes: messages from dying cells
Ramesh Kakarla et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2020)
aCLS cancers: Genomic and epigenetic changes transform the cell of origin of cancer into a tumorigenic pathogen of unicellular organization and lifestyle
Vladimir F. Niculescu
GENE (2020)
Senescence and senotherapeutics: a new field in cancer therapy
Vassilios Myrianthopoulos et al.
PHARMACOLOGY & THERAPEUTICS (2019)
The role of heterogeneous environment and docetaxel gradient in the emergence of polyploid, mesenchymal and resistant prostate cancer cells
Ke-Chih Lin et al.
CLINICAL & EXPERIMENTAL METASTASIS (2019)
Flow Cytometric Detection of Newly-formed Breast Cancer Stem Cell-like Cells After Apoptosis Reversal
Yiyue Xu et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2019)
HER2-Targeted Tyrosine Kinase Inhibitors Cause Therapy-Induced-Senescence in Breast Cancer Cells
Martina S. J. McDermott et al.
CANCERS (2019)
Leukocyte-Cancer Cell Fusion-Genesis of a Deadly Journey
Greggory S. Laberge et al.
CELLS (2019)
Polyploid Giant Cancer Cells (PGCCs): The Evil Roots of Cancer
Junsong Chen et al.
CURRENT CANCER DRUG TARGETS (2019)
Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathway
Mahendra Seervi et al.
CELLULAR ONCOLOGY (2019)
Syncytin 1, CD9, and CD47 regulating cell fusion to form PGCCs associated with cAMP/PKA and JNK signaling pathway
Fei Fei et al.
CANCER MEDICINE (2019)
Patterns of Early p21 Dynamics Determine Proliferation-Senescence Cell Fate after Chemotherapy
Chien-Hsiang Hsu et al.
CELL (2019)
Cancer cell fusion: a potential target to tackle drug-resistant and metastatic cancer cells
Clara Fernandes et al.
DRUG DISCOVERY TODAY (2019)
Tumor Microenvironment and Cell Fusion
Erhui Jiang et al.
BIOMED RESEARCH INTERNATIONAL (2019)
A Unique Morphological Phenotype in Chemoresistant Triple-Negative Breast Cancer Reveals Metabolic Reprogramming and PLIN4 Expression as a Molecular Vulnerability
Isabelle Sirois et al.
MOLECULAR CANCER RESEARCH (2019)
Polyploid giant cancer cells: Unrecognized actuators of tumorigenesis, metastasis, and resistance
Sarah R. Amend et al.
PROSTATE (2019)
Formation of Polyploid Giant Cancer Cells Involves in the Prognostic Value of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer
Fei Fei et al.
JOURNAL OF ONCOLOGY (2019)
The Systemic-Evolutionary Theory of the Origin of Cancer (SETOC): A New Interpretative Model of Cancer as a Complex Biological System
Antonio Mazzocca
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Adaptive mutability of colorectal cancers in response to targeted therapies
Mariangela Russo et al.
SCIENCE (2019)
Dormant, quiescent, tolerant and persister cells: Four synonyms for the same target in cancer
Francois M. Vallette et al.
BIOCHEMICAL PHARMACOLOGY (2019)
Diversity of the Senescence Phenotype of Cancer Cells Treated with Chemotherapeutic Agents
Agnieszka Bojko et al.
CELLS (2019)
To the edge of cell death and back
Yi-Nan Gong et al.
FEBS JOURNAL (2019)
Targeting Cancer Cell Dormancy
Ariadna Recasens et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2019)
Novel roles of apoptotic caspases in tumor repopulation, epigenetic reprogramming, carcinogenesis, and beyond
Ruya Zhao et al.
CANCER AND METASTASIS REVIEWS (2018)
A Distinct Oncogenerative Multinucleated Cancer Cell Serves as a Source of Stemness and Tumor Heterogeneity
David Diaz-Carballo et al.
CANCER RESEARCH (2018)
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Lorenzo Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2018)
Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells
Min Zhou et al.
INTERNATIONAL JOURNAL OF CANCER (2018)
Endoreplication: The Good, the Bad, and the Ugly
Zhiqiang Shu et al.
TRENDS IN CELL BIOLOGY (2018)
Two-Step Senescence-Focused Cancer Therapies
Cynthia J. Sieben et al.
TRENDS IN CELL BIOLOGY (2018)
Evolution of oncogenic signatures of mutation hotspots in tyrosine kinases supports the atavistic hypothesis of cancer
Weiran Chen et al.
SCIENTIFIC REPORTS (2018)
Apoptosis Reversal Promotes Cancer Stem Cell-Like Cell Formation
Yiyue Xu et al.
NEOPLASIA (2018)
Roles of Polyploid/Multinucleated Giant Cancer Cells in Metastasis and Disease Relapse Following Anticancer Treatment
Razmik Mirzayans et al.
CANCERS (2018)
The Biology and Therapeutic Implications of Tumor Dormancy and Reactivation
Amit S. Yadav et al.
FRONTIERS IN ONCOLOGY (2018)
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
Anastasis: recovery from the brink of cell death
Ho Man Tang et al.
ROYAL SOCIETY OPEN SCIENCE (2018)
Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival
Charles E. Gast et al.
SCIENCE ADVANCES (2018)
Viability Assessment Following Anticancer Treatment Requires Single-Cell Visualization
Razmik Mirzayans et al.
CANCERS (2018)
Unconventional Ways to Live and Die: Cell Death and Survival in Development, Homeostasis, and Disease
Swapna A. Gudipaty et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 34 (2018)
Molecular mechanisms of biogenesis of apoptotic exosome-like vesicles and their roles as damage-associated molecular patterns
Soo Jeong Park et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Improving anticancer drug development begins with cell culture: misinformation perpetrated by the misuse of cytotoxicity assays
Alan Eastman
ONCOTARGET (2017)
Do Multiwell Plate High Throughput Assays Measure Loss of Cell Viability Following Exposure to Genotoxic Agents?
Razmik Mirzayans et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome
Razmik Mirzayans et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Multinucleated Giant Cancer Cells Produced in Response to Ionizing Radiation Retain Viability and Replicate Their Genome
Razmik Mirzayans et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
A molecular signature for anastasis, recovery from the brink of apoptotic cell death
Gongping Sun et al.
JOURNAL OF CELL BIOLOGY (2017)
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
Matthew J. Hangauer et al.
NATURE (2017)
Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors
Anna S. Trigos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Cell-cell fusion as a mechanism of DNA exchange in cancer
Stephen C. Searles et al.
Oncotarget (2017)
Essential roles of Caspase-3 in facilitating Myc-induced genetic instability and carcinogenesis
Ian M. Cartwright et al.
ELIFE (2017)
Cancer adaptations: Atavism, de novo selection, or something in between?
Frederic Thomas et al.
BIOESSAYS (2017)
Self-inflicted DNA double-strand breaks sustain tumorigenicity and stemness of cancer cells
Xinjian Liu et al.
CELL RESEARCH (2017)
Multinucleated polyploidy drives resistance to Docetaxel chemotherapy in prostate cancer
Karuna Mittal et al.
BRITISH JOURNAL OF CANCER (2017)
Dying glioma cells establish a proangiogenic microenvironment through a caspase 3 dependent mechanism
Xiao Feng et al.
CANCER LETTERS (2017)
Premature aging/senescence in cancer cells facing therapy: good or bad?
Llilians Calvo Gonzalez et al.
BIOGERONTOLOGY (2016)
Resistance to cancer chemotherapy as an atavism? (retrospective on DOI 10.1002/bies.201300170)
Mark Vincent
BIOESSAYS (2016)
Fusion with stem cell makes the hepatocellular carcinoma cells similar to liver tumor-initiating cells
Ran Wang et al.
BMC CANCER (2016)
Is Senescence Reversible?
Shweta Chakradeo et al.
CURRENT DRUG TARGETS (2016)
Therapeutic resistance and cancer recurrence mechanisms: Unfolding the story of tumour coming back
Mohammad Javad Dehghan Esmatabadi et al.
JOURNAL OF BIOSCIENCES (2016)
Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach
L. Flanagan et al.
CELL DEATH & DISEASE (2016)
Tumor Budding, Micropapillary Pattern, and Polyploidy Giant Cancer Cells in Colorectal Cancer: Current Status and Future Prospects
Shiwu Zhang et al.
STEM CELLS INTERNATIONAL (2016)
The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival?
Razmik Mirzayans et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Cell Fusion in the War on Cancer: A Perspective on the Inception of Malignancy
Jeffrey L. Platt et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
The Dark Side of Cell Fusion
Daniel Bastida-Ruiz et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness
Jianguo Xue et al.
BMC CANCER (2015)
Radiation-induced homotypic cell fusions of innately resistant glioblastoma cells mediate their sustained survival and recurrence
Ekjot Kaur et al.
CARCINOGENESIS (2015)
Dormant Cells: The Original Cause of Tumor Recurrence and Metastasis
Jie Li et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2015)
Spontaneous γH2AX Foci in Human Solid Tumor-Derived Cell Lines in Relation to p21WAF1 and WIP1 Expression
Razmik Mirzayans et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
The number of polyploid giant cancer cells and epithelial-mesenchymal transition-related proteins are associated with invasion and metastasis in human breast cancer
Fei Fei et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2015)
The reverse evolution from multicellularity to unicellularity during carcinogenesis
Han Chen et al.
NATURE COMMUNICATIONS (2015)
A Fraction of CD133+CNE2 Cells Is Made of Giant Cancer Cells with Morphological Evidence of Asymmetric Mitosis
Qingping Jiang et al.
JOURNAL OF CANCER (2015)
Strategies for Tracking Anastasis, A Cell Survival Phenomenon that Reverses Apoptosis
Ho Lam Tang et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2015)
Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence
Grazyna Mosieniak et al.
NEOPLASIA (2015)
Imaging Caspase-3 Activation as a Marker of Apoptosis-Targeted Treatment Response in Cancer
Delphine L. Chen et al.
MOLECULAR IMAGING AND BIOLOGY (2015)
Polyploid giant cancer cells with budding and the expression of cyclin E, S-phase kinase-associated protein 2, stathmin associated with the grading and metastasis in serous ovarian tumor
Hongcheng Lv et al.
BMC CANCER (2014)
Coming Full Circle-From Endless Complexity to Simplicity and Back Again
Robert A. Weinberg
CELL (2014)
HepG2 cells recovered from apoptosis show altered drug responses and invasiveness
Shan-Shan Wang et al.
HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL (2014)
Caspase 3 Promotes Surviving Melanoma Tumor Cell Growth after Cytotoxic Therapy
Anne L. Donato et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2014)
Generation of cancer stem-like cells through the formation of polyploid giant cancer cells
S. Zhang et al.
ONCOGENE (2014)
Fusion of bone marrow-derived cells with cancer cells: metastasis as a secondary disease in cancer
John M. Pawelek
CHINESE JOURNAL OF CANCER (2014)
Size does matter: why polyploid tumor cells are critical drug targets in the war on cancer
Jermaine Coward et al.
FRONTIERS IN ONCOLOGY (2014)
Mechanisms of disseminated cancer cell dormancy: an awakening field
Maria Soledad Sosa et al.
NATURE REVIEWS CANCER (2014)
Three steps to the immortality of cancer cells: senescence, polyploidy and self-renewal
Jekaterina Erenpreisa et al.
CANCER CELL INTERNATIONAL (2013)
Vital dyes and virtual deaths
M. Husmann
CELL DEATH AND DIFFERENTIATION (2013)
Measuring apoptosis by microscopy and flow cytometry
Conor M. Henry et al.
METHODS (2013)
Cell fusion promotes chemoresistance in metastatic colon carcinoma
V. Carloni et al.
ONCOGENE (2013)
β-lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity
A. Gutierrez et al.
NATURE COMMUNICATIONS (2013)
Spontaneous Formation of Tumorigenic Hybrids between Breast Cancer and Multipotent Stromal Cells Is a Source of Tumor Heterogeneity
Germana Rappa et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
p53-Mediated Senescence Impairs the Apoptotic Response to Chemotherapy and Clinical Outcome in Breast Cancer
James G. Jackson et al.
CANCER CELL (2012)
Cell survival, DNA damage, and oncogenic transformation after a transient and reversible apoptotic response
Ho Lam Tang et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
Spontaneous Cancer-Stromal Cell Fusion as a Mechanism of Prostate Cancer Androgen-Independent Progression
Ruoxiang Wang et al.
PLOS ONE (2012)
Dying cell clearance and its impact on the outcome of tumor radiotherapy
Kirsten Lauber et al.
FRONTIERS IN ONCOLOGY (2012)
Role of p16(INK4A) in Replicative Senescence and DNA Damage-Induced Premature Senescence in p53-Deficient Human Cells
Razmik Mirzayans et al.
BIOCHEMISTRY RESEARCH INTERNATIONAL (2012)
Co-cultivation of murine BMDCs with 67NR mouse mammary carcinoma cells give rise to highly drug resistant cells
Christa Nagler et al.
CANCER CELL INTERNATIONAL (2011)
EGF Receptor Inhibition Radiosensitizes NSCLC Cells by Inducing Senescence in Cells Sustaining DNA Double-Strand Breaks
Meng Wang et al.
CANCER RESEARCH (2011)
Characterization of hybrid cells derived from spontaneous fusion events between breast epithelial cells exhibiting stem-like characteristics and breast cancer cells
Thomas Dittmar et al.
CLINICAL & EXPERIMENTAL METASTASIS (2011)
Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy
Qian Huang et al.
NATURE MEDICINE (2011)
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
Jean -Philippe Coppe et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Senescent cells as a source of inflammatory factors for tumor progression
Albert R. Davalos et al.
CANCER AND METASTASIS REVIEWS (2010)
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
Sreenath V. Sharma et al.
CELL (2010)
Mitochondria and cell death: outer membrane permeabilization and beyond
Stephen W. G. Tait et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
MOS, aneuploidy and the ploidy cycle of cancer cells
J. Erenpreisa et al.
ONCOGENE (2010)
Autophagy, senescence and tumor dormancy in cancer therapy
David A. Gewirtz
AUTOPHAGY (2009)
Reversibility of apoptosis in cancer cells
H. L. Tang et al.
BRITISH JOURNAL OF CANCER (2009)
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
G. Kroemer et al.
CELL DEATH AND DIFFERENTIATION (2009)
Induction of senescence with doxorubicin leads to increased genomic instability of HCT1 16 cells
Malgorzata A. Sliwinska et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2009)
Endopolyploidy in irradiated p53-deficient tumour cell lines: Persistence of cell division activity in giant cells expressing Aurora-B kinase
Jekaterina Erenpreisa et al.
CELL BIOLOGY INTERNATIONAL (2008)
Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy
Pierre-Emmanuel Puig et al.
CELL BIOLOGY INTERNATIONAL (2008)
Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells:: Implications for chemotherapy
Elvira Crescenzi et al.
CLINICAL CANCER RESEARCH (2008)
Active caspase 3 and DNA fragmentation as markers for apoptotic cell death in primary and metastatic liver tumours
Eva Karamitopoulou et al.
PATHOLOGY (2007)
Co-repression of mismatch repair gene expression by hypoxia in cancer cells: Role of the Myc/Max network
Ranjit S. Bindra et al.
CANCER LETTERS (2007)
Mutation as a stress response and the regulation of evolvability
Rodrigo S. Galhardo et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2007)
The NCI60 human tumour cell line anticancer drug screen
Robert H. Shoemaker
NATURE REVIEWS CANCER (2006)
Sulforhodamine B colorimetric assay for cytotoxicity screening
Vanicha Vichai et al.
NATURE PROTOCOLS (2006)
Mitotic catastrophe results in cell death by caspase-dependent and caspase-independent mechanisms
S Mansilla et al.
CELL CYCLE (2006)
Budded karyoplasts from multinucleated fibroblast cells contain centrosomes and change their morphology to mitotic cells
KH Walen
CELL BIOLOGY INTERNATIONAL (2005)
Neosis - a paradigm of self-renewal in cancer
R Rajaraman et al.
CELL BIOLOGY INTERNATIONAL (2005)
A switch from high-fidelity to error-prone DNA double-strand break repair underlies stress-induced mutation
RG Ponder et al.
MOLECULAR CELL (2005)
Neosis - A novel type of cell division in cancer
M Sundaram et al.
CANCER BIOLOGY & THERAPY (2004)
Death receptor signals to mitochondria
R Khosravi-Far et al.
CANCER BIOLOGY & THERAPY (2004)
Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells
VT Mihaylova et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Adaptive mutations, mutator DNA polymerases and genetic change strategies of pathogens
GJ McKenzie et al.
CURRENT OPINION IN MICROBIOLOGY (2001)
Caspase-3 activity as a prognostic factor in colorectal carcinoma
LE Jonges et al.
LABORATORY INVESTIGATION (2001)
The SOS response regulates adaptive mutation
GJ McKenzie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2
M Haraguchi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Polyploid giant cells provide a survival mechanism for p53 mutant cells after DNA damage
TM Illidge et al.
CELL BIOLOGY INTERNATIONAL (2000)
Release of mitotic descendants by giant cells from irradiated Burkitt's lymphoma cell lines
JA Erenpreisa et al.
CELL BIOLOGY INTERNATIONAL (2000)
分享论文
