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Tight junction strand formation by claudin-10 isoforms and claudin-10a/-10b chimeras
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Polar and charged extracellular residues conserved among barrier-forming claudins contribute to tight junction strand formation
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Differential Stability of the Crystallographic Interfaces of Mu- and Kappa-Opioid Receptors
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Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions
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Claudin-2 pore function requires an intramolecular disulfide bond between two conserved extracellular cysteines
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Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux
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Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics
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PLOS COMPUTATIONAL BIOLOGY (2013)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Lessons from Free Energy Simulations of δ-Opioid Receptor Homodimers Involving the Fourth Transmembrane Helix
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Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity
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Structure-Function Studies of Claudin Extracellular Domains by Cysteine-scanning Mutagenesis
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Free Energy and Kinetics of Conformational Transitions from Voronoi Tessellated Milestoning with Restraining Potentials
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Molecular Basis for Cation Selectivity in Claudin-2-based Paracellular Pores: Identification of an Electrostatic Interaction Site
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Tricellulin Forms a Barrier to Macromolecules in Tricellular Tight Junctions without Affecting Ion Permeability
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MOLECULAR BIOLOGY OF THE CELL (2009)
Interferon-gamma and tumor necrosis factor-alpha disrupt epithelial barrier function by altering lipid composition in membrane microdomains of tight junction
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CLINICAL IMMUNOLOGY (2008)
Formation of tight junction: determinants of homophilic interaction between classic claudins
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FASEB JOURNAL (2008)
The density of small tight junction pores varies among cell types and is increased by expression of claudin-2
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The MARTINI force field: Coarse grained model for biomolecular simulations
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JOURNAL OF PHYSICAL CHEMISTRY B (2007)
Two splice variants of claudin-10 in the kidney create paracellular pores with different ion selectivities
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Calculation of absolute protein-ligand binding free energy from computer simulations
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Depletion of Caco-2 cell cholesterol disrupts barrier function by altering the detergent solubility and distribution of specific tight-junction proteins
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BIOCHEMICAL JOURNAL (2005)
Computing time scales from reaction coordinates by milestoning
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JOURNAL OF CHEMICAL PHYSICS (2004)
Functional modeling of tight junctions in intestinal cell monolayers using polyethylene glycol oligomers
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AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2001)
Conversion of Zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells
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