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Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function
Suleiman Massarweh et al.
CANCER RESEARCH (2008)
The complexity of mitogen-activated protein kinases (MAPKs) made simple
M. Krishna et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
EXEL-7647 inhibits mutant forms of ErbB2 associated with lapatinib resistance and neoplastic transformation
Torsten Trowe et al.
CLINICAL CANCER RESEARCH (2008)
Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation
Lijian Hui et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
An Autocrine VEGF/VEGFR2 and p38 Signaling Loop Confers Resistance to 4-Hydroxytamoxifen in MCF-7 Breast Cancer Cells
Reidun Aesoy et al.
MOLECULAR CANCER RESEARCH (2008)
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
James Bean et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
Javier A. Menendez et al.
NATURE REVIEWS CANCER (2007)
p38α suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway
Lijian Hui et al.
NATURE GENETICS (2007)
Delineation of molecular mechanisms of sensitivity to lapatinib in breast cancer cell lines using global gene expression profiles
Priti S. Hegde et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Interfering with MAP kinase docking interactions - Implications and perspective for the p38 route
Federico Mayor et al.
CELL CYCLE (2007)
p38α MAP kinase as a sensor of reactive oxygen species in tumorigenesis
Ignacio Dolado et al.
CANCER CELL (2007)
V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors
OM Grbovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells
B Nicke et al.
MOLECULAR CELL (2005)
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
W Pao et al.
PLOS MEDICINE (2005)
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
S Kobayashi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Role of the p38 mitogen-activated protein kinase pathway in the generation of the effects of imatinib mesylate (STI571) in BCR-ABL-expressing cells
S Parmar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
P38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor
XM Qi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence
WP Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)