4.7 Article

Biogenic synthesis of Mn-Ag co-doped FeO(Fe1-2xMnxAgx) nanoparticles: As an effective disinfectant and anticancer agent

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INORGANIC CHEMISTRY COMMUNICATIONS
卷 112, 期 -, 页码 -

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ELSEVIER
DOI: 10.1016/j.inoche.2019.107712

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Magnetic nanoparticles; Green synthesis; Cytotoxicity; Nanosize

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A nature-friendly method was developed to synthesize novel Mn-Ag co-doped FeO nanoparticles using Solarium Trilobatwn leaf extract. Crystallinity nature, size, morphology and chemical composition were analysed from high resolution characterisation techniques such as XRD-XPS, FESEM-EDS, SEM-TEM, ICP-CHNS, UV-visible, FTIR, FT-Raman and Zeta potential. X-ray diffraction evident the cubic phase of the nanoparticles, FESEM images gives the glimpse of agglomerated nano-spherical shaped FeO particles and ICP measures the Fe content in the samples. Mn-Ag co-doped FeO nanoparticles showed a convincing result for antibacterial activity and also acted as a powerful factor in MIT assay performed against MCF-7 cells compared to HeLa cells and also it doesn't show high effectivity against Vero cells. Hence, this Mn-Ag Co-doped FeO nanoparticles can bring a modulation in anticancer drug delivery system.

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