相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes
Kow Essuman et al.
CURRENT BIOLOGY (2018)
Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections
Mira C. Patel et al.
MBIO (2018)
Triaryl Pyrazole Toll-Like Receptor Signaling Inhibitors: Structure-Activity Relationships Governing Pan- and Selective Signaling Inhibitors
Julie A. Pollock et al.
CHEMMEDCHEM (2018)
Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins
Sirish K. Ippagunta et al.
SCIENCE SIGNALING (2018)
The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration
Kow Essuman et al.
NEURON (2017)
Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling
Mark M. Hughes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection
Laure Perrin-Cocon et al.
SCIENTIFIC REPORTS (2017)
Redox sensitivity of the MyD88 immune signaling adapter
Benjamin Stottmeier et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
Novel strategies for targeting innate immune responses to influenza
K. A. Shirey et al.
MUCOSAL IMMUNOLOGY (2016)
MD-2 is required for disulfide HMGB1-dependent TLR4 signaling
Huan Yang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen
Mark A. Olson et al.
SCIENTIFIC REPORTS (2015)
A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza
Wenji Piao et al.
CELL REPORTS (2015)
The Brucella TIR domain containing proteins BtpA and BtpB have a structural WxxxE motif important for protection against microtubule depolymerisation
Christine Felix et al.
CELL COMMUNICATION AND SIGNALING (2014)
Molecular Interactions in Interleukin and Toll-like Receptor Signaling Pathways
Greg A. Snyder et al.
CURRENT PHARMACEUTICAL DESIGN (2014)
Crystal Structures of the Toll/Interleukin-1 Receptor (TIR) Domains from the Brucella Protein TcpB and Host Adaptor TIRAP Reveal Mechanisms of Molecular Mimicry
Greg A. Snyder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Mechanism of Bacterial Interference with TLR4 Signaling by Brucella Toll/Interleukin-1 Receptor Domain-containing Protein TcpB
Mohammed Alaidarous et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Crystal Structure of TIR Domain of TLR6 Reveals Novel Dimeric Interface of TIR-TIR Interaction for Toll-Like Receptor Signaling Pathway
Tae-ho Jang et al.
JOURNAL OF MOLECULAR BIOLOGY (2014)
Assembly and localization of Toll-like receptor signalling complexes
Nicholas J. Gay et al.
NATURE REVIEWS IMMUNOLOGY (2014)
The TLR4 antagonist Eritoran protects mice from lethal influenza infection
Kari Ann Shirey et al.
NATURE (2013)
Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli
Greg A. Snyder et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Suppression of TLR Signaling by Targeting TIR domain-Containing Proteins
Ota Fekonja et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2012)
Targeting Toll-like Receptor (TLR) Signaling by Toll/Interleukin-1 Receptor (TIR) Domain-containing Adapter Protein/MyD88 Adapter-like (TIRAP/Mal)-derived Decoy Peptides
Leah A. Couture et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A Small Molecule That Mimics the BB-loop in the Toll Interleukin-1 (IL-1) Receptor Domain of MyD88 Attenuates Staphylococcal Enterotoxin B-induced Pro-inflammatory Cytokine Production and Toxicity in Mice
Teri L. Kissner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
Eugene Valkov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model
K. Takashima et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Costimulation Modulation Uncouples Protection from Immunopathology in Memory T Cell Responses to Influenza Virus
John R. Teijaro et al.
JOURNAL OF IMMUNOLOGY (2009)
The pathology of influenza virus infections
Jeffery K. Taubenberger et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)
TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain
Tomohiro Kawamoto et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
The crystal structure of the human Toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer
Tomas Nyman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism
Kari Ann Shirey et al.
JOURNAL OF IMMUNOLOGY (2008)
Pyogenic bacterial infections in humans with MyD88 deficiency
Horst von Bernuth et al.
SCIENCE (2008)
Clustal W and clustal X version 2.0
M. A. Larkin et al.
BIOINFORMATICS (2007)
Therapeutic effects of TAK-242, a novel selective Toll-like receptor 4 signal transduction inhibitor, in mouse endotoxin shock model
Takukyu Sha et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Pivotal Advance:: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound
Maria Loiarro et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Cell-penetrating TIR BB loop decoy peptides: a novel class of TLR signaling inhibitors and a tool to study topology of TIR-TIR interactions
Vladimir Y. Toshchakov et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2007)
Analysis of TLR4 polymorphic variants: New insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling
Prasad Rallabhandi et al.
JOURNAL OF IMMUNOLOGY (2006)
A novel cyclohexene derivative, ethyl (6R)-6-[N-(2-chloro-4-fluorophenyl) sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), selectively inhibits toll-like receptor 4-mediated cytokine production through suppression of intracellular signaling
M Ii et al.
MOLECULAR PHARMACOLOGY (2006)
Pathogen recognition and innate immunity
S Akira et al.
CELL (2006)
Susceptibilities of antiviral-resistant influenza viruses to novel neuraminidase inhibitors
VP Mishin et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Differential involvement of BB loops of Toll-IL-1 resistance (TIR) domain-containing adapter proteins in TLR4-versus TLR2-mediated signal transduction
VU Toshchakov et al.
JOURNAL OF IMMUNOLOGY (2005)
Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL
JA Khan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2
X Tao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains
YW Xu et al.
NATURE (2000)
分享论文
