4.8 Editorial Material

In Situ Support of ILC Precursors

期刊

IMMUNITY
卷 52, 期 2, 页码 207-209

出版社

CELL PRESS
DOI: 10.1016/j.immuni.2020.01.011

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资金

  1. Crohn's and Colitis Foundation fellowship [608975]
  2. National Institutes of Health (NIH) [R01AI143842, R01AI123368, R01AI145989, R21CA249274, U01AI095608]
  3. NIAID Mucosal Immunology Studies Team (MIST)
  4. Searle Scholars Program
  5. American Asthma Foundation Scholar Award
  6. Burroughs Wellcome Fund
  7. Wade F.B. Thompson/Cancer Research Institute (CRI) CLIP Investigator grant
  8. Meyer Cancer Center Collaborative Research Initiative
  9. Roberts Institute for Research in IBD

向作者/读者索取更多资源

Innate lymphoid cells (ILCs) are tissue-resident lymphocytes that promote immunity to pathogens at mucosal barriers, but the mechanisms regulating their development within tissues remain poorly understood. In this issue of Immunity, Oherle et al. identify a niche in the neonatal airway where stromal cell-derived insulin-like growth factor 1 (IGF1) supports the proliferation of ILC precursors and protects from infection.

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