期刊
BRITISH JOURNAL OF CANCER
卷 115, 期 6, 页码 703-706出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/bjc.2016.127
关键词
Colorectal cancer; neoplasm; biological markers; matrix metalloproteinases; MMPs; blood plasma; blood serum
类别
资金
- Swedish LUA/ALF foundation
- Sahlgrenska University Hospital [ALFGBG-143521]
- Swedish Cancer Society [130355]
- Inga-Britt and Arne Lundberg Foundation [388/11]
- Scientific Advisory Board, Halland Region, Sweden
Background: There are inconsistencies in the use of serum or plasma when analysing the matrix metalloproteinases (MMPs) as diagnostic or prognostic markers. The purpose of this study was to compare the concentration of MMP-1, -2, -7, -8, -9 and -13 in serum vs plasma samples. Methods: Blood samples were obtained from sixty-five men and women. Samples were analysed for levels of MMPs in corresponding citrate plasma and serum. Results: All MMPs expressed higher concentration in serum compared with plasma (P<0.01). There were no differences between genders. Conclusions: Present study demonstrated significant differences regarding concentrations of some MMPs using plasma vs serum. We conclude that future studies regarding MMPs as biological markers in cancer should consider the use of citrate plasma instead of serum.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据