相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。A dominant activating RAC2 variant associated with immunodeficiency and pulmonary disease
B. M. Smits et al.
CLINICAL IMMUNOLOGY (2020)
Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects
Amy P. Hsu et al.
BLOOD (2019)
Gene therapy targeting haematopoietic stem cells for inherited diseases: progress and challenges
Marina Cavazzana et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
Heterozygous activating mutation in RAC2 causes infantile-onset combined immunodeficiency with susceptibility to viral infections
Svetlana O. Sharapova et al.
CLINICAL IMMUNOLOGY (2019)
A monoallelic activating mutation in RAC2 resulting in a combined immunodeficiency
Vassilios Lougaris et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)
Classical and Emerging Regulatory Mechanisms of Cytokinesis in Animal Cells
Vikash Verma et al.
BIOLOGY-BASEL (2019)
International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity
Capucine Picard et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2018)
Regulation of Hematopoietic Cell Development and Function Through Phosphoinositides
Mila Elich et al.
FRONTIERS IN IMMUNOLOGY (2018)
RAC2-P38 MAPK-dependent NADPH oxidase activity is associated with the resistance of quiescent cells to ionizing radiation
Hailong Pei et al.
CELL CYCLE (2017)
The mitochondrial respiratory chain is essential for haematopoietic stem cell function
Elena Anso et al.
NATURE CELL BIOLOGY (2017)
Depletion of SAM50 Specifically Targets BCR-ABL-Expressing Leukemic Stem and Progenitor Cells by Interfering with Mitochondrial Functions
Marta E. Capala et al.
STEM CELLS AND DEVELOPMENT (2016)
Dynamic actin cycling through mitochondrial subpopulations locally regulates the fission-fusion balance within mitochondrial networks
Andrew S. Moore et al.
NATURE COMMUNICATIONS (2016)
Human RAG mutations: biochemistry and clinical implications
Luigi D. Notarangelo et al.
NATURE REVIEWS IMMUNOLOGY (2016)
RAC2 loss-of-function mutation in 2 siblings with characteristics of common variable immunodeficiency
Omar K. Alkhairy et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2015)
Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2
Marta E. Capala et al.
PLOS ONE (2015)
AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages
E. Six et al.
CELL DEATH & DISEASE (2015)
Severe combined immunodeficiencies and related disorders
Alain Fischer et al.
NATURE REVIEWS DISEASE PRIMERS (2015)
Stem cells and the impact of ROS signaling
Carolina L. Bigarella et al.
DEVELOPMENT (2014)
DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity
Qian Zhang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Hematopoietic-specific Rho GTPases Rac2 and RhoH and human blood disorders
Anja Troeger et al.
EXPERIMENTAL CELL RESEARCH (2013)
Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells
Ramesh C. Nayak et al.
IMMUNOLOGICAL REVIEWS (2013)
Excess F-actin mechanically impedes mitosis leading to cytokinesis failure in X-linked neutropenia by exceeding Aurora B kinase error correction capacity
Dale A. Moulding et al.
BLOOD (2012)
Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors
Margaret Nieborowska-Skorska et al.
BLOOD (2012)
Redundant functions of Rac GTPases in inner ear morphogenesis
Cynthia M. Grimsley-Myers et al.
DEVELOPMENTAL BIOLOGY (2012)
Human T-Lymphoid Progenitors Generated in a Feeder-Cell-Free Delta-Like-4 Culture System Promote T-Cell Reconstitution in NOD/SCID/γc-/- Mice
Christian Reimann et al.
STEM CELLS (2012)
Human phagocyte defect caused by a Rac2 mutation detected by means of neonatal screening for T-cell lymphopenia
Deborah Accetta et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)
Structural Insights into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2
Tom D. Bunney et al.
MOLECULAR CELL (2009)
Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness
Chantal Lagresle-Peyrou et al.
NATURE GENETICS (2009)
Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2
Ulrich Pannicke et al.
NATURE GENETICS (2009)
Inhibition of Rac by the GAP Activity of Centralspindlin Is Essential for Cytokinesis
Julie C. Canman et al.
SCIENCE (2008)
Haematopoietic progenitor cells utilise conventional PKC to suppress PKB/Akt activity in response to c-Kit stimulation
Charlotte E. Edling et al.
BRITISH JOURNAL OF HAEMATOLOGY (2007)
Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases
Y Gu et al.
SCIENCE (2003)
Rac2 regulation of phospholipase C-β2 activity and mode of membrane interactions in intact cells
D Illenberger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells
Y Gu et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
The TRQQKRP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localization
W Tao et al.
BLOOD (2002)
Immune reconstitution without graft-versus-host disease after haemopoietic stem-cell transplantation:: a phase 1/2 study
I André-Schmutz et al.
LANCET (2002)
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
DR Ambruso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI
K Scheffzek et al.
NATURE STRUCTURAL BIOLOGY (2000)
分享论文
