Development of a SPME-GC-MS/MS method for the determination of some contaminants from food contact material in beverages

The development and validation of a simple, low-cost, and sensitive method for the determination of nine compounds expected in beverages and vinegar as a result of migration from food contact material (parabens, phenolic antioxidants, sulfonamide plasticizer, and flame retardant) is presented. The analytes were preconcentrated using solid-phase microextraction and analyzed by gas chromatography - tandem mass spectrometry. The method required no derivatization procedure and an affordable chemical was used as internal standard. The LODs were in the range of 0.005-0.2 mu g/L, the relative standard deviations 0.8-5.4%, and the mean recoveries 98-109%. Different alcoholic beverages and vinegars were analyzed. A crown cap migration study using several food simulants was conducted for 6 months. Moreover, migration from a home brewing plastic fermenter in a time span of 4 weeks was studied. Analyte concentrations up to 2220.99 mu g/L were detected in real samples and up to 4.75 mu g/L in migration experiments.