期刊
FISH & SHELLFISH IMMUNOLOGY
卷 95, 期 -, 页码 190-194出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fsi.2019.10.020
关键词
Darkbarbel catfish; Aeromonas hydrophila; Antioxidant; Resistance diseases; mTOR and NF-kB signaling pathway
资金
- National Nature Science Fund for Distinguished Young Scholars of China [41625002]
- National Natural Science Foundation Young of China [31700432]
- National Natural Science Foundation of China [31700432, 31470550, 81500493, 31400386, 51778114]
- Postdoctoral Science Foundation Project of China and Heilongjiang Province [2018M641797, 2018HLJ6578]
- Opening Project of Key Laboratory of Soil Conservation and Rehabilitation in Heilongjiang Province [SPR2018001]
- Natural Science Foundation of Guangdong Province [2015A030313098]
- Application Technology Research and Development Projects of Harbin [2016RAXXJ103]
- MOA Modern Agricultural Talents Support Project
The improvement of resistance diseases, antioxidant and nonspecific immunity responses for Darkbarbel catfish by dietary residual pomegranate was investigated. The number of pathogenic bacteria and cumulative mortality of Darkbarbel catfish under 15-45% groups were decreased compared with control group (CK). Bioactive substances (polyphenols and vitamin) in residual pomegranate enhanced AKP, ACP, phagocytic, SOD, CAT activities through up-regulating AKP, ACP, SOD, CAT genes expression levels. Theoretical analysis showed bioactive substances regulated these genes expressions and enzyme activities as stimulus signal, component, active center. Moreover, residual pomegranate improved mTOR and NF-kB signaling pathway responses. Thus, residual pomegranate inhibited Aeromonas hydrophila that increased resistance to diseases. This technology completed the solid waste recovery and the Darkbarbel catfish growth performance simultaneously.
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