期刊
FEMS YEAST RESEARCH
卷 20, 期 2, 页码 -出版社
OXFORD UNIV PRESS
DOI: 10.1093/femsyr/foaa008
关键词
Saccharomyces; Hanseniaspora; Phaffia; Biotechnology; Wild yeast
资金
- CONICET [PIP11220130100392CO]
- Universidad Nacional del Comahue [B199]
- National Science Foundation [DEB-1442148, DEB-1442113]
- Howard Hughes Medical Institute through the James H. Gilliam Fellowships for Advanced Study program
- USDA National Institute of Food and Agriculture (Hatch Project) [1020204]
- DOE Great Lakes Bioenergy Research Center [DE-SC0018409]
- Pew Charitable Trusts
- Office of the Vice Chancellor for Research and Graduate Education
- Wisconsin Alumni Research Foundation
- European Union [747775]
- Marie Curie Actions (MSCA) [747775] Funding Source: Marie Curie Actions (MSCA)
Genomic studies of yeasts from the wild have increased considerably in the past few years. This revolution has been fueled by advances in high-throughput sequencing technologies and a better understanding of yeast ecology and phylogeography, especially for biotechnologically important species. The present review aims to first introduce new bioinformatic tools available for the generation and analysis of yeast genomes. We also assess the accumulated genomic data of wild isolates of industrially relevant species, such as Saccharomyces spp., which provide unique opportunities to further investigate the domestication processes associated with the fermentation industry and opportunistic pathogenesis. The availability of genome sequences of other less conventional yeasts obtained from the wild has also increased substantially, including representatives of the phyla Ascomycota (e.g. Hanseniaspora) and Basidiomycota (e.g. Phaffia). Here, we review salient examples of both fundamental and applied research that demonstrate the importance of continuing to sequence and analyze genomes of wild yeasts.
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