期刊
DISABILITY AND REHABILITATION
卷 43, 期 22, 页码 3251-3259出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09638288.2020.1731853
关键词
Modified fatigue impact scale (MFIS); psychometric properties; multiple sclerosis (MS); validity; reliability; Arabic Translation
资金
- King Abdulaziz City for Science and Technology [AP-35-380]
The study translated and validated the MFIS-A in Arabic for patients with MS, showing good validity and reliability in assessing fatigue in MS patients. The MFIS-A differentiated healthy participants from patients with high sensitivity and specificity.
Purpose: To translate and validate the modified fatigue impact scale into Arabic (MFIS-A) in patients with multiple sclerosis (MS). Methods: A total of 116 patients with relapsing remitting MS and 59 healthy participants were recruited. Fifty patients filled the MFIS-A twice with one week difference. Reliability was assessed by measuring Cronbach's alpha and intraclass correlation coefficient (ICC). The MFIS-A was correlated with the fatigue severity scale (FSS), the vitality domain of the Short Form 36 (SF-36V), the fatigue visual analogue scale (VAS-F), and the Beck Depression Inventory II (BDI-II) to assess validity. Dimensionality of the MFIS-A was investigated. A receiver operating characteristic (ROC) curve analysis was done and specificity and sensitivity were calculated. Results: Factor analysis (based on 116 patients) revealed that the MFIS-A consists of two subscales: the physical/social and the cognitive subscales. The MFIS-A showed excellent test-retest reliability (ICC = 0.920) and internal consistency (Cronbach's alpha = 0.968). The minimal detectable change with 95% confidence interval was 14.68 (32.0%). The MFIS-A showed strong positive correlation with FSS and BDI-II, moderate positive correlation with VAS-F, negative moderate correlation with SF-36V, and weak correlation with EDSS. The MFIS-A differentiated healthy participants from patients with 79.3% sensitivity and 89.8% specificity. Conclusions: The MFIS-A showed good validity and reliability indicating its usefulness as an assessment measure for patients with MS.
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