期刊
CURRENT PHARMACEUTICAL DESIGN
卷 25, 期 45, 页码 4763-4770出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1381612825666191210152156
关键词
Stroke; Middle Cerebral Artery Occlusion (MCAO); nutrients deprivation; Oxygen-glucose Deprivation (OGD); signaling; mTORC1; AMPK
资金
- MINECO/FEDER [SAF2015-70368-R]
- CAM [B2017/BMD-3700]
- Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas (CIBERNED)
- Proyectos Colaborativos CIBERNED [PI2016/01]
- Fundacion Ramon Areces to CBMSO
- Fondos FEDER
- program: FORMACION DE TALENTO HUMANO DE ALTO NIVEL., from Universidad del Tolima, Ibague, Colombia
- I+D+i-RETOS- [RTI2018-096303-B-C1]
Stroke is an important cause of death and disability, and it is the second leading cause of death worldwide. In humans, middle cerebral artery occlusion (MCAO) is the most common cause of ischemic stroke. The damage occurs due to the lack of nutrients and oxygen contributed by the blood flow. The present review aims to analyze to what extent the lack of each of the elements of the system leads to damage and which mechanisms are unaffected by this deficiency. We believe that the specific analysis of the effect of lack of each component could lead to the emergence of new therapeutic targets for this important brain pathology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据