期刊
BRAIN BEHAVIOR AND IMMUNITY
卷 51, 期 -, 页码 1-11出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.bbi.2015.06.012
关键词
Tai Chi; Qigong; Yoga; Meditation; Inflammation; Review
资金
- UCLA CTSI [UL1TR000124]
- Cousins Center for Psychoneuroimmunology [P30-AG028748]
- UCLA Claude D. Pepper Older Americans Independence Center
- Breast Cancer Research Foundation
- [RO1 CA160427]
- [RO1 CA160245]
- [RO1 AG034588]
- [RO1 AG026364]
- [RO1 CA119159]
- [RO1 HL095799]
- [RO1 DA032922]
- [P30 AG028748]
- NATIONAL CANCER INSTITUTE [R01CA160245, R01CA119159, R01CA160427] Funding Source: NIH RePORTER
- NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES [UL1TR000124] Funding Source: NIH RePORTER
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL079955] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [R01AG034588, P30AG028748] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON DRUG ABUSE [R01DA032922] Funding Source: NIH RePORTER
The use of mind-body therapies, including Tai Chi, Qigong, yoga, and meditation, has grown steadily in recent years. These approaches have been shown to be effective in reducing symptoms and improving quality of life, and research has begun to examine the impact of these therapies on biological processes, including inflammation. A review of 26 randomized controlled trials was conducted to describe the effects of mind-body therapies (MBTs) on circulating, cellular, and genomic markers of inflammation. This qualitative evaluation showed mixed effects of MBTs on circulating inflammatory markers, including CRP and IL-6, and on measures of stimulated cytokine production. More consistent findings were seen for genomic markers, with trials showing decreased expression of inflammation-related genes and reduced signaling through the proinflammatory transcription factor NF-kappa B. Potential mechanisms for these effects are discussed, including alterations in neuroendocrine, neural, and psychological and behavioral processes. (C) 2015 Elsevier Inc. All rights reserved.
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