期刊
CRITICAL REVIEWS IN MICROBIOLOGY
卷 45, 期 5-6, 页码 539-547出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/1040841X.2019.1621795
关键词
Bacterial translocation mechanisms; acute pancreatitis; 16S rDNA
类别
资金
- Luzhou-Southwest Medical University Joint Project [2017LZXNYD-J31, 2017LZXNYD-T11]
- Southwest Medical University Youth Project [2017-ZRQN-078]
- Affiliated Hospital Youth Project of Southwest Medical University [2017-QB-2, 2017-QB-3]
Bacterial translocation is a phenomenon in which live bacteria or their products cross the intestinal barrier to other organs or the circulatory system. Gut translocation of bacteria has been reported in both animal models, and clinical trials often accompany acute pancreatitis and are believed to be linked to patient outcome, especially in severe acute pancreatitis. Therefore, the mechanisms of intestinal bacterial translocation in acute pancreatitis have become a topic of interest in recent years. This review discusses Bacterial translocation in acute pancreatitis, identifies possible mechanisms of action, and provides an overview of the methods used to detect Bacterial translocation in acute pancreatitis. This review also highlights areas that require further research.
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