相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Resveratrol treatment in patients with polycystic ovary syndrome decreased pro-inflammatory and endoplasmic reticulum stress markers
Samaneh Brenjian et al.
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2020)
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary
Donna K. Arnett et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)
The association between lipid-lowering drugs and circulating concentration of PCSK9
Zeljko Reiner
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2019)
Resveratrol downregulates PCSK9 expression and attenuates steatosis through estrogen receptor α-mediated pathway in L02 cells
Yi Jing et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2019)
The year in cardiology 2018: prevention
Zeljko Reiner et al.
EUROPEAN HEART JOURNAL (2019)
Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia
Deepak L. Bhatt et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Role of PCSK9 in the Development of Mouse Periodontitis Before and After Treatment: A Double-Edged Sword
Hua Ling Sun et al.
JOURNAL OF INFECTIOUS DISEASES (2018)
Resveratrol attenuates type 2 diabetes mellitus by mediating mitochondrial biogenesis and lipid metabolism via Sirtuin type 1
Ming-Ming Cao et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2018)
Chitosan oligosaccharides enhance lipid droplets via down-regulation of PCSK9 gene expression in HepG2 cells
Xi Yang et al.
EXPERIMENTAL CELL RESEARCH (2018)
Pinostrobin Inhibits Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) Gene Expression through the Modulation of FoxO3a Protein in HepG2 Cells
Wan-Yun Gao et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)
PCSK9 inhibition in the management of familial hypercholesterolemia
Masatsune Ogura
JOURNAL OF CARDIOLOGY (2018)
The Role of Nutraceuticals in Statin Intolerant Patients
Maciej Banach et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)
Berberine Could Ameliorate Cardiac Dysfunction via Interfering Myocardial Lipidomic Profiles in the Rat Model of Diabetic Cardiomyopathy
Shifen Dong et al.
FRONTIERS IN PHYSIOLOGY (2018)
siRNA delivery system based on magnetic nanovectors: Characterization and stability evaluation
Mohammed Abdelrahman et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Potential role of lycopene in targeting proprotein convertase subtilisin/kexin type-9 to combat hypercholesterolemia
Sahir Sultan Alvi et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Effects of a New Nutraceutical Formulation (Berberine, Red Yeast Rice and Chitosan) on Non-HDL Cholesterol Levels in Individuals with Dyslipidemia: Results from a Randomized, Double Blind, Placebo-Controlled Study
Valentina Spigoni et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Curcumin Protects Against Intestinal Origin Endotoxemia in Rat Liver Cirrhosis by Targeting PCSK9
Yu Cai et al.
JOURNAL OF FOOD SCIENCE (2017)
Epigallocatechin gallate induces an up-regulation of LDL receptor accompanied by a reduction of PCSK9 via the annexin A2-independent pathway in HepG2 cells
Kohei Kitamura et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2017)
Promoting Effect of Pinostrobin on the Proliferation, Differentiation, and Mineralization of Murine Pre-osteoblastic MC3T3-E1 Cells
Chengbo Gu et al.
MOLECULES (2017)
Lipid-lowering nutraceuticals in clinical practice: position paper from an International Lipid Expert Panel
Arrigo F. G. Cicero et al.
NUTRITION REVIEWS (2017)
Prevention of cardiovascular disease in patients with familial hypercholesterolaemia: The role of PCSK9 inhibitors
Ivan Pecin et al.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2017)
PCSK9 signaling pathways and their potential importance in clinical practice
Michal Wicinski et al.
EPMA JOURNAL (2017)
Lycopene amends LPS induced oxidative stress and hypertriglyceridemia via modulating PCSK-9 expression and Apo-CIII mediated lipoprotein lipase activity
Sahir Sultan Alvi et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
New role of PCSK9 in atherosclerotic inflammation promotion involving the TLR4/NF-κB pathway
Zhi-Han Tang et al.
ATHEROSCLEROSIS (2017)
Long-term low dose dietary resveratrol supplement reduces cardiovascular structural and functional deterioration in chronic heart failure in rats
Ismayil Ahmet et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2017)
A nutraceutical approach (Armolipid Plus) to reduce total and LDL cholesterol in individuals with mild to moderate dyslipidemia: Review of the clinical evidence
Vivencio Barrios et al.
ATHEROSCLEROSIS SUPPLEMENTS (2017)
Suppressor of Cytokine Signaling-3 (SOCS-3) Induces Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Expression in Hepatic HepG2 Cell Line
Massimiliano Ruscica et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Local effects of human PCSK9 on the atherosclerotic lesion
Ilaria Giunzioni et al.
JOURNAL OF PATHOLOGY (2016)
A review on biological sources, chemistry and pharmacological activities of pinostrobin
Neeraj K. Patel et al.
NATURAL PRODUCT RESEARCH (2016)
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Alberico L. Catapano et al.
EUROPEAN HEART JOURNAL (2016)
Enhanced pro-protein convertase subtilisin/kexin type 9 expression by C-reactive protein through p38MAPK-HNF1α pathway in HepG2 cells
Chuan-Jue Cui et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2016)
Addition of aspirin to a fish oil-rich diet decreases inflammation and atherosclerosis in ApoE-null mice
Alexander V. Sorokin et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2016)
Fish oil alleviated high-fat diet-induced non-alcoholic fatty liver disease via regulating hepatic lipids metabolism and metaflammation: a transcriptomic study
Fahu Yuan et al.
LIPIDS IN HEALTH AND DISEASE (2016)
Lipid-modifying effects of nutraceuticals: An evidence-based approach
Amirhossein Sahebkar et al.
NUTRITION (2016)
DIFFERENTIAL EXPRESSION OF PCSK9 MODULATES INFECTION, INFLAMMATION, AND COAGULATION IN A MURINE MODEL OF SEPSIS
Dhruva J. Dwivedi et al.
SHOCK (2016)
Marine n-3 polyunsaturated fatty acids lower plasma proprotein convertase subtilisin kexin type 9 levels in pre- and postmenopausal women: A randomised study
Christina B. Graversen et al.
VASCULAR PHARMACOLOGY (2016)
Genetic Variants of LDLR and PCSK9 Associated with Variations in Response to Antihypercholesterolemic Effects of Armolipid Plus with Berberine
Isabel De Castro-Oros et al.
PLOS ONE (2016)
Lipopolysaccharide Is Cleared from the Circulation by Hepatocytes via the Low Density Lipoprotein Receptor
Elena Topchiy et al.
PLOS ONE (2016)
Hemodynamic Shear Stress via ROS Modulates PCSK9 Expression in Human Vascular Endothelial and Smooth Muscle Cells and Along the Mouse Aorta
Zufeng Ding et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
PCSK9 Induces CD36 Degradation and Affects Long-Chain Fatty Acid Uptake and Triglyceride Metabolism in Adipocytes and in Mouse Liver
Annie Demers et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2015)
Adverse Effects of Statins - Myths and Reality
Iveta Simic et al.
CURRENT PHARMACEUTICAL DESIGN (2015)
Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols, and Berberine) in Patients with Low-Moderate Risk Hypercholesterolemia: A Double-Blind, Placebo-Controlled Study
Stefano Gonnelli et al.
CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL (2015)
PCSK9 inhibitors - past, present and future
Zeljko Reiner
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2015)
Aspirin regulates hepatocellular lipid metabolism by activating AMPK signaling pathway
Zhenxing He et al.
JOURNAL OF TOXICOLOGICAL SCIENCES (2015)
Inhibition of proprotein convertase subtilisin/kexin type 9: A novel mechanism of berberine and 8-hydroxy dihydroberberine against hyperlipidemia
Liu De-liang et al.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2015)
Inhibition of PCSK9 Transcription by Berberine Involves Down-regulation of Hepatic HNF1 α Protein Expression through the Ubiquitin-Proteasome Degradation Pathway
Bin Dong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Variable effects of gender and Western diet on lipid and glucose homeostasis in aged PCSK9-deficient C57BL/6 mice
Majambu Mbikay et al.
JOURNAL OF DIABETES (2015)
Association of plasma PCSK9 levels with white blood cell count and its subsets in patients with stable coronary artery disease
Sha Li et al.
ATHEROSCLEROSIS (2014)
PCSK9: A Key Modulator of Cardiovascular Health
Nabil G. Seidah et al.
CIRCULATION RESEARCH (2014)
Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin
Susan Kuhnast et al.
JOURNAL OF LIPID RESEARCH (2014)
Curcumin enhances cell-surface LDLR level and promotes LDL uptake through downregulation of PCSK9 gene expression in HepG2 cells
Mi-Hsueh Tai et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2014)
Resistance and intolerance to statins
Z. Reiner
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2014)
Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network
Jerome C. Nwachukwu et al.
ELIFE (2014)
PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells
Emile Levy et al.
ATHEROSCLEROSIS (2013)
Resveratrol and Clinical Trials: The Crossroad from In Vitro Studies to Human Evidence
Joao Tomé-Carneiro et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
Cerebroprotective potential of resveratrol through anti-oxidant and anti-inflammatory mechanisms in rats
Prabhakar Orsu et al.
JOURNAL OF NEURAL TRANSMISSION (2013)
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Can Mediate Degradation of the Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1)
Maryssa Canuel et al.
PLOS ONE (2013)
Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels
Nicola Ferri et al.
ATHEROSCLEROSIS (2012)
Fish oil - How does it reduce plasma triglycerides?
Gregory C. Shearer et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2012)
Epigallocatechin gallate changes mRNA expression level of genes involved in cholesterol metabolism in hepatocytes
Tsuyoshi Goto et al.
BRITISH JOURNAL OF NUTRITION (2012)
PCSK9 regulates neuronal apoptosis by adjusting ApoER2 levels and signaling
Kai Kysenius et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Protective Effects of Pinostrobin on β-Amyloid-Induced Neurotoxicity in PC12 Cells
Yan-Fang Xian et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2012)
Gene Inactivation of Proprotein Convertase Subtilisin/Kexin Type 9 Reduces Atherosclerosis in Mice
Maxime Denis et al.
CIRCULATION (2012)
PCSK9 siRNA suppresses the inflammatory response induced by oxLDL through inhibition of NF-κB activation in THP-1-derived macrophages
Zhihan Tang et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2012)
Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline
Lars Berglund et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Omega-3 supplementation and non-alcoholic fatty liver disease: A systematic review and meta-analysis
Helen M. Parker et al.
JOURNAL OF HEPATOLOGY (2012)
Discovery of a New Role of Human Resistin in Hepatocyte Low-Density Lipoprotein Receptor Suppression Mediated in Part by Proprotein Convertase Subtilisin/Kexin Type 9
Michelle Melone et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2012)
PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway
Chun-Yan Wu et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2012)
Circulating Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Regulates VLDLR Protein and Triglyceride Accumulation in Visceral Adipose Tissue
Anna Roubtsova et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)
Janus kinase activation by cytokine oncostatin M decreases PCSK9 expression in liver cells
Aiqin Cao et al.
JOURNAL OF LIPID RESEARCH (2011)
Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment
Purusotam Basnet et al.
MOLECULES (2011)
Carotenoids and Their Isomers: Color Pigments in Fruits and Vegetables
Hock-Eng Khoo et al.
MOLECULES (2011)
Protective effect of lycopene on serum cholesterol and blood pressure: Meta-analyses of intervention trials
Karin Ried et al.
MATURITAS (2011)
Strong induction of PCSK9 gene expression through HNF1α and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters
Bin Dong et al.
JOURNAL OF LIPID RESEARCH (2010)
Curcumin suppresses expression of low-density lipoprotein (LDL) receptor, leading to the inhibition of LDL-induced activation of hepatic stellate cells
Qiaohua Kang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Plasma PCSK9 Is Associated with Age, Sex, and Multiple Metabolic Markers in a Population-Based Sample of Children and Adolescents
Alexis Baass et al.
CLINICAL CHEMISTRY (2009)
Curcumin Inhibits srebp-2 Expression in Activated Hepatic Stellate Cells in Vitro by Reducing the Activity of Specificity Protein-1
Qiaohua Kang et al.
ENDOCRINOLOGY (2009)
PCSK9 Impedes Hepatitis C Virus Infection In Vitro and Modulates Liver CD81 Expression
Patrick Labonte et al.
HEPATOLOGY (2009)
Hepatocyte Nuclear Factor 1α Plays a Critical Role in PCSK9 Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine
Hai Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Antioxidant Activities of Extracts and Main Components of Pigeonpea [Cajanus cajan (L.) Millsp.] Leaves
Nan Wu et al.
MOLECULES (2009)
Berberine decreases PCSK9 expression in HepG2 cells
Jamie Cameron et al.
ATHEROSCLEROSIS (2008)
Inflammation stimulates the expression of PCSK9
Kenneth R. Feingold et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Involvement of anti-inflammatory heme oxygenase-1 in the inhibitory effect of curcumin on the expression of pro-inflammatory inducible nitric oxide synthase in RAW264.7 macrophages
Ki Mo Kim et al.
BIOMEDICINE & PHARMACOTHERAPY (2008)
N-3 polyunsaturated fatty acid regulation of hepatic gene transcription
Donald B. Jump
CURRENT OPINION IN LIPIDOLOGY (2008)
Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9
Sanae Kourimate et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Genome-wide expression analysis of cells expressing gain of function mutant D374Y-PCSK9
Trine Ranheim et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Dietary resveratrol alters lipid metabolism-related gene expression of mice on an atherogenic diet
Jiyun Ahn et al.
JOURNAL OF HEPATOLOGY (2008)
Curcumin Up-Regulates LDL Receptor Expression via the Sterol Regulatory Element Pathway in HepG2 Cells
Xiaobing Dou et al.
PLANTA MEDICA (2008)
Sterol-dependent regulation of proprotein convertase subtilisin/kexin type 9 expression by sterol-regulatory element binding protein-2
Hyun Jeong Jeong et al.
JOURNAL OF LIPID RESEARCH (2008)
The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2
Steve Poirier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The self-inhibited structure of full-length PCSK9 at 1.9 Å reveals structural homology with resistin within the C-terminal domain
Eric N. Hampton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The C679X mutation in PCSK9 is present and lowers blood cholesterol in a Southern African population
Amanda J. Hooper et al.
ATHEROSCLEROSIS (2007)
Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice
Thomas A. Lagace et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Policosanol inhibits cholesterol synthesis in hepatoma cells by activation of AMP-kinase
Dev K. Singh et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Modulation of cholesterol metabolism by the green tea polyphenol (-)-epigallocatechin gallate in cultured human liver (HepG2) cells
CA Bursill et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)
Mechanisms of gene silencing by double-stranded RNA
G Meister et al.
NATURE (2004)
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
SM Grundy et al.
CIRCULATION (2004)
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
WJ Kong et al.
NATURE MEDICINE (2004)
Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host
W Khovidhunkit et al.
JOURNAL OF LIPID RESEARCH (2004)
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
M Abifadel et al.
NATURE GENETICS (2003)
Pinostrobin from honey and Thai ginger (Boesenbergia pandurata):: A potent flavonoid inducer of mammalian phase 2 chemoprotective and antioxidant enzymes
JF Fahey et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2002)
Curcuma longa extract supplementation reduces oxidative stress and attenuates aortic fatty streak development in rabbits
JL Quiles et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2002)
An hydroalcoholic extract of Curcuma longa lowers the apo B/apo A ratio -: Implications for atherogenesis prevention
A Ramírez-Boscá et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2000)
Effects of tea consumption on nutrition and health
CS Yang et al.
JOURNAL OF NUTRITION (2000)
Infection and inflammation induce LDL oxidation in vivo
RA Memon et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2000)
分享论文
