期刊
CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY
卷 50, 期 19, 页码 2016-2059出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/10643389.2019.1692611
关键词
Antibiotic resistant bacteria; antibiotic resistance genes; quantitative microbial risk assessment
资金
- Japan Society for the Promotion of Science [18K13855, 16H01782]
- The Sanitation Value Chain: Designing Sanitation Systems as Eco-Community Value System Project from Research Institute for Humanity and Nature (RIHN) [14200107]
- Grants-in-Aid for Scientific Research [18K13855] Funding Source: KAKEN
Aquatic environments are identified as an ideal setting for acquisition and dissemination of antibiotic resistance, and human exposure to antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) in aquatic environments may pose an additional health risk. Quantitative microbial risk assessment (QMRA) has been suggested as a suitable method to evaluate and quantify this health risk. However, information about the exposure to ARB and ARGs in aquatic environments is lacking for many scenarios and dose-response models regarding the ARB infections are not developed yet. This review summarizes the current knowledge regarding the ARB and ARGs in aquatic environments and highlights the challenging questions remaining to be answered to better forecast the health risks caused by ARB and ARGs in water environments. The questions include what are the missing information needed to quantify the human health risks caused by exposing to ARB and ARGs in aquatic environments? what are the suitable markers to evaluate the ARB/ARGs contamination in aquatic environments? how frequently do the ARG selection and propagation occur in aquatic environments? and are there any unknown hot spots? Studies on the above topics will contribute to better management of antibiotic resistance dissemination in water environments and its risks on human health.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据