期刊
CHINESE PHYSICS B
卷 29, 期 3, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/1674-1056/ab7441
关键词
delay; fractal; bistability; electromagnetic induction
资金
- National Natural Science Foundation of China [11772242]
- China Postdoctoral Science Foundation [2018M631140]
Previous studies have observed that electromagnetic induction can seriously affect the electrophysiological activity of the nervous system. Considering the role of astrocytes in regulating neural firing, we studied a simple neuron-astrocyte coupled system under electromagnetic induction in response to different types of external stimulation. Both the duration and intensity of the external stimulus can induce different modes of electrical activity in this system, and thus the neuronal firing patterns can be subtly controlled. When the external stimulation ceases, the neuron will continue to fire for a long time and then reset to its resting state. In this study, delay is defined as the delayed time from the firing state to the resting state, and it is highly sensitive to changes in the duration or intensity of the external stimulus. Meanwhile, the self-similarity embodied in the aforementioned sensitivity can be quantified by fractal dimension. Moreover, a hysteresis loop of calcium activity in the astrocyte is observed in the specific interval of the external stimulus when the stimulus duration is extended to infinity, since astrocytic calcium or neuron electrical activity in the resting state or during periodic oscillation depends on the initial state. Finally, the regulating effect of electromagnetic induction in this system is considered. It is clarified that the occurrence of delay depends purely on the existence of electromagnetic induction. This model can reveal the dynamic characteristics of the neuron-astrocyte coupling system with magnetic induction under external stimulation. These results can provide some insights into the effects of electromagnetic induction and stimulation on neuronal activity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据