期刊
CHINESE MEDICAL JOURNAL
卷 133, 期 4, 页码 483-493出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/CM9.0000000000000652
关键词
Scoliosis; Pathogenesis; Etiology; Mesenchymal stem cells
资金
- National Natural Science Foundation of China [81272054, 81171673]
- Beijing Talent Fund [2015000021223ZK27]
- Beijing Nova program Grant [2014A019]
Etiology of adolescent idiopathic scoliosis (AIS), a complicated three-dimensional spinal deformity with early-onset, receives continuous attention but remains unclear. To gain an insight into AIS pathogenesis, this review searched PubMed database up to June 2019, using key words or medical subject headings terms including adolescent idiopathic scoliosis, scoliosis, pathogenesis, etiology, genetics, mesenchymal stem cells, and their combinations, summarized existing literatures and categorized the theories or hypothesis into nine aspects. These aspects include bone marrow mesenchymal stem cell studies, genetic studies, tissue analysis, spine biomechanics measurements, neurologic analysis, hormone studies, biochemical analysis, environmental factor analysis, and lifestyle explorations. These categories could be a guidance for further etiology or treatment researches to gain inspiration.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据