期刊
CHINESE CHEMICAL LETTERS
卷 31, 期 8, 页码 2129-2132出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2020.01.034
关键词
Drug detection; Calix[6]arene derivative; GO complexes; Quartz crystal microbalance sensor; Schiff base interaction
资金
- National Natural Science Foundation of China [61527818]
- Shanghai Municipal Education Commission
- (Peak Discipline Construction Program)
In order to improve the convenience and sensitivity of amphetamines drug testing and reduce the threat of drugs to humans, we have designed a QCM gas sensor to detect amine-containing drugs. The sensing material is designed based on the chemical nature of amine drugs. The sensing mechanism is derived from a reversible Schiff base interaction between the amino group of the drug and the carbonyl group of the novel calix[6]arene derivatives as well as the hydrogen bond interaction between amino group and hydroxyl. The new composite material was well characterized by different analytical techniques including H-1 nuclear magnetic resonance (H-1-NMR), fourier transform infrared spectroscopy (FT-IR), scanning electronic microscopy (SEM), transmission electron microscope (TEM), Raman spectra, powder X-ray diffraction, etc. The sensing experiments were conducted by coating the composite onto quartz crystal microbalance (QCM) transducers. The experimental results indicated that the novel calixarene derivatives and their GO complexes based on the design have excellent selectivity, high sensitivity and repeatability to beta-phenylethylamine. (C) 2020 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据