期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 26, 期 15, 页码 3194-3196出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.202000656
关键词
automated synthesis; high-throughput screening; industrial chemistry; robotics; synthetic methods
High-throughput experimentation (HTE) is a growing, enabling technology that allows the execution of large, parallel sets of experiments. Often, automation is required to dose compounds on milligram to sub-milligram scale, to run many parallel reactions, and to analyse large datasets. Unique approaches to screen design, implementation, and analysis are required, distinct from traditional synthetic organic chemistry. The discipline also presents a profitable opportunity for individual scientists to learn about and explore fields adjacent to chemistry, including data science, robotics and equipment engineering, and computer programming. This perspective presents the author's viewpoints on the field of HTE, its implementation within a chemistry career, and the automated future of organic chemistry technology.
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