期刊
CHEMISTRY & BIODIVERSITY
卷 17, 期 2, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201900040
关键词
mangrove plant; endophytic fungus; indole derivative; cytotoxicity; biological activity
资金
- National Natural Science Foundation of China [21772210, 41406187]
- Open Research Fund Program of Beijing Key Lab of Plant Resource Research and Development, Beijing Technology and Business University [PRRD-2017-ZD3]
- Guangzhou Scientific Research Project of 2014 [2014 J4100212]
- Fund for the Development of Science and Technology of Guangdong Province [2014 A030313765]
- China Scholarship Council [201608260116]
- Guangdong MEPP Funds [GDME-2018 C010, GDOE[2019]A28, 2019-017]
- National Natural Science, Foundation of China [21772210, 81741154, 81741158, 41776169]
- Institution of South China Sea Ecology and Environmental Engineering, CAS [ISEE2018-PY04]
A new indole derivative colletoindole A (1), along with two new indole derivatives (2 and 3) and one known compound acropyrone (4) were isolated from cultures of Colletotrichum tropicale SCSIO 41022 derived from a mangrove plant Kandelia candel. The structures of 1-4 were determined by analysis of NMR and MS data. The cytotoxicity of 1, 2 and 4, and the COX-2 inhibitory activity of 1 and 2 were evaluated.
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