期刊
CARDIOLOGY IN THE YOUNG
卷 30, 期 2, 页码 180-187出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1047951119003184
关键词
CHDs; attention-deficit/hyperactivity disorder; Ventricular Septal Defect; Transposition of the Greater Arteries; Tetralogy of Fallot
资金
- Jascha Foundation
- Ville Heises grant
- Elsass Foundation
- Hede Nielsen Foundation
- Candys Foundation
Background: Children with complex CHD are at risk for psychopathology such as severe attention-deficit/ hyperactivity disorder symptoms after congenital heart surgery. Objective: The aim of this study was to investigate if children with Ventricular Septal Defect, Transposition of Great Arteries, or Tetralogy of Fallot have an increased occurrence of attention-deficit/hyperactivity disorder symptoms compared with the background population and to investigate differences between the three CHDs in terms of occurrence and appearance of attention-deficit/hyperactivity disorder symptoms. Method: A national register-based survey was conducted, including children aged 10-16 years with surgically corrected CHDs without genetic abnormalities and syndromes. The Attention-Deficit/Hyperactivity Disorder-Rating Scale questionnaires were filled in by parents and school teachers. Results: In total, 159 out of 283 questionnaires were completed among children with CHDs and compared with age- and sex-matched controls. Children with CHDs had significantly increased inattention scores (p = 0.009) and total attention-deficit/hyperactivity disorder scores (p = 0.008) compared with controls. Post hoc analyses revealed that children with Tetralogy of Fallot had significantly higher inattention scores compared with children both with Ventricular Septal Defect (p=0.043) and controls (p = 0.004). Conclusion: Attention-deficit/hyperactivity disorder symptoms and inattention symptoms were significantly more frequent among children aged 10-16 years with CHDs, in particular in children with corrected Tetralogy of Fallot.
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