期刊
BIOCHEMICAL PHARMACOLOGY
卷 173, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bcp.2020.113828
关键词
Noncommunicable disease; Natural compounds; Antiaging; Nuclear factor erythroid 2-related factor 2; Polyunsaturated fatty acid; Polyphenol
资金
- COST (European Cooperation in Science and Technology) [CA16112]
- NRF of South Korea [019R1A2C1009231, 2011-0030001]
- South Korea Brain Korea (BK21) PLUS program
- Creative-Pioneering Researchers Program at Seoul National University (SNU), South Korea [370C-20160062]
Natural compounds are known to display therapeutic potential against a variety of chronic conditions, including cancer and inflammation. The efficacy of these natural substances can be associated with numerous molecular scaffolds present in extracts of living organisms, both terrestrial and marine. Recently, investigators have identified the ability of natural compounds to trigger immunogenic cell death and subsequent activation of the adaptive immune system. Such findings indicate that the full therapeutic potential of natural products has yet to be defined, and further investigations on such agents will continue to yield novel drug candidates.
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