期刊
APPLIED RADIATION AND ISOTOPES
卷 157, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.apradiso.2019.109032
关键词
Boron nitride nanotubes; Rare-earth; Bioapplication; Therapy; Diagnosis; Theranostics
类别
资金
- FAPEMIG (Fundacao de Amparo Pesquisa do Estado de Minas Gerais) [TEC -APQ-01897-16]
- CAPES (Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior)
- CNEN (Comissao Nacional de Energia Nuclear)
- CNPq (Conselho Nacional de Desenvolvimento Cientifico e Tecnologico) [305475/2015-0]
Boron nitride nanotubes (BNNTs) have been growing in notoriety in the development of systems aiming bioapplications. In this work we conducted an investigation about the mechanisms involved in the incorporation of samarium and gadolinium in BNNTs. The process was performed by the reduction of samarium and gadolinium oxides (Sm2O and Gd2O, respectively) in the presence of NH3 gas (witch decomposes into N-2 and H-2) at high temperatures. Various characterization techniques were conducted to elucidate how Sm and Gd are introduced into the BNNT structure. Biological in vitro assays were performed with human fibroblasts and a human osteosarcoma cell line (SAOS-2). Our results show that the studied systems have high potential for biomedical application and can be used as non-invasive imaging agents, such as scintigraphy radiotracers or as magnetic resonance imaging (MRI) contrast medium, being able to promote the treatment of many types of tumors simultaneously to their diagnosis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据