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Bariatric Surgery as a Long-Term Treatment for Type 2 Diabetes/Metabolic Syndrome

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DOI: 10.1146/annurev-med-053117-123246

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metabolic surgery; bariatric surgery; type 2 diabetes; cardiovascular risk factor; weight loss; diabetes remission

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Metabolic surgery is increasingly becoming recognized as a more effective treatment for patients with type 2 diabetes (T2D) and obesity as compared to lifestyle modification and medical management alone. Both observational studies and clinical trials have shown metabolic surgery to result in sustained weight loss (20-30%), T2D remission rates ranging from 23% to 60%, and improvement in cardiovascular risk factors such as hypertension and dyslipidemia. Metabolic surgery is cost-effective and relatively safe, with perioperative risks and mortality comparable to low-risk procedures such as cholecystectomy, hysterectomy, and appendectomy. International diabetes and medical organizations have endorsed metabolic surgery as a standard treatment for T2D with obesity.

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