期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 59, 期 23, 页码 8937-8940出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.202002289
关键词
asymmetric catalysis; ligand design; silanes; spirocompounds; synthetic methods
资金
- National Natural Science Foundation of China [21821002] Funding Source: Medline
- Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences Funding Source: Medline
Reported here is the development of a class of chiral spirosilabiindane scaffolds by Rh-catalyzed asymmetric double hydrosilation, for the first time. Enantiopure SPSiOL (spirosilabiindane diol), a new type of chiral building block for the preparation of various chiral ligands and catalysts, was readily prepared on greater than 10 gram scale using this protocol. The potential of this new spirosilabiindane scaffold in asymmetric catalysis was preliminarily demonstrated by development of the corresponding monodentate phosphoramidite ligands (SPSiPhos), which were used in both a Rh-catalyzed hydrogenation and a Pd-catalyzed intramolecular carboamination.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据