期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 59, 期 15, 页码 5890-5900出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201911477
关键词
2D nanomaterials; cancer theranostics; photothermal therapy; synergistic therapy
资金
- National Natural Science Foundation of China [21822802, 51772018, 51572271]
- National Key Research and Development Program of China [2016YFA0201500]
- Fundamental Research Funds for the Central Universities [XK1901, buctrc201915, PYBZ1825, XK1802-8]
Two-dimensional (2D) nanomaterials are currently explored as novel photothermal agents because of their ultrathin structure, high specific surface area, and unique optoelectronic properties. In addition to single photothermal therapy (PTT), 2D nanomaterials have demonstrated significant potential in PTT-based synergistic therapies. In this Minireview, we summarize the recent progress in 2D nanomaterials for enhanced photothermal cancer therapy over the last five years. Their unique optical properties, typical synthesis methods, and surface modification are also covered. Emphasis is placed on their PTT and PTT-synergized chemotherapy, photodynamic therapy, and immunotherapy. The major challenges of 2D photothermal agents are addressed and the promising prospects are also presented.
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