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E. L. Simpson et al.
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Nicola A. Hanania et al.
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D. Kaur et al.
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Strategies targeting the IL-4/IL-13 axes in disease
Richard D. May et al.
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Naina Gour et al.
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Mario Castro et al.
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Arash Grakoui et al.
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Jennifer D. Hamilton et al.
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Lung niches for the generation and maintenance of tissue-resident memory T cells
D. L. Turner et al.
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Kristin G. Anderson et al.
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Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes
Lynn E. Macdonald et al.
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Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice
Andrew J. Murphy et al.
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Pathogenic memory type Th2 cells in allergic inflammation
Yusuke Endo et al.
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C. Edward Rose et al.
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Kelly D. Stone et al.
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Erika Wissinger et al.
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Lin Ying Liu et al.
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Clinical relevance of airway remodelling in airway diseases
A. L. James et al.
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Eosinophil trafficking in allergy and asthma
Helene F. Rosenberg et al.
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Mast cells express IL-13αR1: IL-13 promotes human lung mast cell proliferation and FcεRI expression
D. Kaur et al.
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A Lorentz et al.
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The re-emergence pivotal cell in of the mast cell as a asthma pathogenesis
CE Brightling et al.
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JR Johnson et al.
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EJ Sundberg et al.
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T Biedermann et al.
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Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma
W Busse et al.
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The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics
M Solèr et al.
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H Hochrein et al.
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IL-4 is a mediator of IL-12p70 induction by human Th2 cells: Reversal of polarized Th2 phenotype by dendritic cells
P Kalinski et al.
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