期刊
BIOMOLECULES
卷 9, 期 11, 页码 -出版社
MDPI
DOI: 10.3390/biom9110730
关键词
Xanthan gum; FT-IR and NMR analysis; X-ray diffraction (XRD) analysis; Caco-2 cells
资金
- Natural Science Foundation of Henan Provincial Education Department [19A180015]
- National Natural Science Foundation of China [31801535]
- Key Laboratory of Wuliangye-flavor liquor solid-state fermentation of China National Light Industry [2017JJ012, 2018JJ017]
- Major Science and Technology Projects in Henan Province [181100211400]
- Doctoral Fund of Zhengzhou University of Light Industry [2016BSJJ018]
In the present work, a low-molecular-weight xanthan gum (LW-XG) was successfully obtained via biodegradation of commercial xanthan by the endophytic fungus Chaetomiumglobosum CGMCC 6882. The monosaccharide composition of LW-XG was glucose, mannose, and glucuronic acid in a molar ratio of 1.63:1.5:1.0. The molecular weight of LW-XG was 4.07 x 10(4) Da and much smaller than that of commercial xanthan (2.95 x 10(6) Da). Antioxidant assays showed that LW-XG had a good scavenging ability on DPPH radicals, superoxide anions, and hydroxyl radicals and good ferric reducing power. Moreover, LW-XG exhibited excellent protective effect on H2O2-injured Caco-2 cells. Results of this work suggested that LW-XG could be used in foods or pharmaceuticals to alleviate and resist the oxidative damage induced by the overproduction of reactive oxygen species.
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