相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The NOD2 signaling in peripheral macrophages contributes to neuropathic pain development
Flavia Santa-Cecilia et al.
PAIN (2019)
Trace levels of peptidoglycan in serum underlie the NOD-dependent cytokine response to endoplasmic reticulum stress
Raphael Molinaro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
NOD1 and NOD2 in inflammation, immunity and disease
Tapas Mukherjee et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2019)
XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures
Kornelia Ellwanger et al.
LIFE SCIENCE ALLIANCE (2019)
Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors
Chalada Suebsuwong et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling
Matous Hrdinka et al.
EMBO JOURNAL (2018)
Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling
Tatiana Goncharov et al.
MOLECULAR CELL (2018)
IAPs Regulate Distinct Innate Immune Pathways to Co-ordinate the Response to Bacterial Peptidoglycans
Che A. Stafford et al.
CELL REPORTS (2018)
Outer Membrane Vesicles From Probiotic and Commensal Escherichia coli Activate NOD1-Mediated Immune Responses in Intestinal Epithelial Cells
Maria-Alexandra Canas et al.
FRONTIERS IN MICROBIOLOGY (2018)
Frontline Science: RIP2 promotes house dust mite-induced allergic airway inflammation
Madelyn H. Miller et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2018)
CARD domain of rat RIP2 kinase: Refolding, solution structure, pH-dependent behavior and protein-protein interactions
Sergey A. Goncharuk et al.
PLOS ONE (2018)
RIP2 filament formation is required for NOD2 dependent NF-κB signalling
Erika Pellegrini et al.
NATURE COMMUNICATIONS (2018)
The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex
Swarupa Panda et al.
NATURE COMMUNICATIONS (2018)
Structural basis of RIP2 activation and signaling
Qin Gong et al.
NATURE COMMUNICATIONS (2018)
Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens
Sylvain Normand et al.
NATURE COMMUNICATIONS (2018)
Interferon gamma boosts the nucleotide oligomerization domain 2-mediated signaling pathway in human dendritic cells in an X-linked inhibitor of apoptosis protein and mammalian target of rapamycin-dependent manner
Tunde Fekete et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2017)
Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation
Erika Pellegrini et al.
PLOS ONE (2017)
Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases
Xiaohui He et al.
ACS MEDICINAL CHEMISTRY LETTERS (2017)
E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP
Pradeep Bist et al.
NATURE COMMUNICATIONS (2017)
Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance
Kenny L. Chan et al.
CELL REPORTS (2017)
Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4
Joseph F. Cavallari et al.
CELL METABOLISM (2017)
The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase
Pamela A. Haile et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
NOD1/NOD2 signaling links ER stress with inflammation
A. Marijke Keestra-Gounder et al.
NATURE (2016)
Proteogenomics connects somatic mutations to signalling in breast cancer
Philipp Mertins et al.
NATURE (2016)
NOD-Like Receptors in Infection, Immunity, and Diseases
Young Keun Kim et al.
YONSEI MEDICAL JOURNAL (2016)
Crystal structure of NOD2 and its implications in human disease
Sakiko Maekawa et al.
NATURE COMMUNICATIONS (2016)
CYLD Limits Lys63-and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling
Matous Hrdinka et al.
CELL REPORTS (2016)
Legionella pneumophila-Derived Outer Membrane Vesicles Promote Bacterial Replication in Macrophages
Anna Lena Jung et al.
PLOS PATHOGENS (2016)
Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity
Adam K. Charnley et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors
Peter Canning et al.
CHEMISTRY & BIOLOGY (2015)
Defective NOD2 peptidoglycan sensing promotes diet-induced inflammation, dysbiosis, and insulin resistance
Emmanuel Denou et al.
EMBO MOLECULAR MEDICINE (2015)
The diverse role of RIP kinases in necroptosis and inflammation
John Silke et al.
NATURE IMMUNOLOGY (2015)
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
Ueli Nachbur et al.
NATURE COMMUNICATIONS (2015)
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
Kate E. Lawlor et al.
NATURE COMMUNICATIONS (2015)
Structural basis of death domain signaling in the p75 neurotrophin receptor
Zhi Lin et al.
ELIFE (2015)
Fusion of Legionella pneumophila outer membrane vesicles with eukaryotic membrane systems is a mechanism to deliver pathogen factors to host cell membranes
Jens Jaeger et al.
CELLULAR MICROBIOLOGY (2015)
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
Alvin Lu et al.
CELL (2014)
The Immune Receptor NOD1 and Kinase RIP2 Interact with Bacterial Peptidoglycan on Early Endosomes to Promote Autophagy and Inflammatory Signaling
Aaron T. Irving et al.
CELL HOST & MICROBE (2014)
NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease
Roberta Caruso et al.
IMMUNITY (2014)
Engagement of Nucleotide-binding Oligomerization Domain-containing Protein 1 (NOD1) by Receptor-interacting Protein 2 (RIP2) Is Insufficient for Signal Transduction
Sophie Mayle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
In Vivo Inhibition of RIPK2 Kinase Alleviates Inflammatory Disease
Justine T. Tigno-Aranjuez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The Molecular Chaperone HSP70 Binds to and Stabilizes NOD2, an Important Protein Involved in Crohn Disease
Vishnu Mohanan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
A Genome-wide Small Interfering RNA (siRNA) Screen Reveals Nuclear Factor-κB (NF-κB)-independent Regulators of NOD2-induced Interleukin-8 (IL-8) Secretion
Neil Warner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies
Stephen M. Condon et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Structural insights into the MDP binding and CARD- CARD interaction in zebrafish ( Danio rerio) NOD2: a molecular dynamics approach
Jitendra Maharana et al.
JOURNAL OF MOLECULAR RECOGNITION (2014)
NOD2 downregulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF6
T. Watanabe et al.
MUCOSAL IMMUNOLOGY (2014)
Endosomes are specialized platforms for bacterial sensing and NOD2 signalling
Norihiro Nakamura et al.
NATURE (2014)
NOD proteins: regulators of inflammation in health and disease
Dana J. Philpott et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Higher-Order Assemblies in a New Paradigm of Signal Transduction
Hao Wu
CELL (2013)
Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling
Rune Busk Damgaard et al.
EMBO MOLECULAR MEDICINE (2013)
Linear ubiquitination-mediated NF-κB regulation and its related disorders
Fuminori Tokunaga
JOURNAL OF BIOCHEMISTRY (2013)
OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling
Berthe Katrine Fiil et al.
MOLECULAR CELL (2013)
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
Shuo Yang et al.
NATURE IMMUNOLOGY (2013)
T Cell Intrinsic NOD2 Is Dispensable for CD8 T Cell Immunity
Gloria H. Y. Lin et al.
PLOS ONE (2013)
Inhibitor of Apoptosis (IAP) Proteins-Modulators of Cell Death and Inflammation
John Silke et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
The Ubiquitin Code
David Komander et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
Mutational analysis of human NOD1 and NOD2 NACHT domains reveals different modes of activation
Birte Zurek et al.
INNATE IMMUNITY (2012)
Proteasomal Degradation of Nod2 Protein Mediates Tolerance to Bacterial Cell Wall Components
Kyoung-Hee Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The Innate Immune Protein Nod2 Binds Directly to MDP, a Bacterial Cell Wall Fragment
Catherine Leimkuhler Grimes et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
Rune Busk Damgaard et al.
MOLECULAR CELL (2012)
Is BID required for NOD signalling?
Ueli Nachbur et al.
NATURE (2012)
The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB
Monika Schneider et al.
NATURE IMMUNOLOGY (2012)
The Tandem CARDs of NOD2: Intramolecular Interactions and Recognition of RIP2
Veronica Fridh et al.
PLOS ONE (2012)
Outer Membrane Vesicles from Brucella abortus Promote Bacterial Internalization by Human Monocytes and Modulate Their Innate Immune Response
Cora N. Pollak et al.
PLOS ONE (2012)
NOD1 Activators Link Innate Immunity to Insulin Resistance
Jonathan D. Schertzer et al.
DIABETES (2011)
Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment
Jacques Amar et al.
EMBO MOLECULAR MEDICINE (2011)
Intrinsic expression of Nod2 in CD4+ T lymphocytes is not necessary for the development of cell-mediated immunity and host resistance to Toxoplasma gondii
Braulia C. Caetano et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands
Joao G. Magalhaes et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Secretory Mediators Regulate Nod2-Induced Tolerance in Human Macrophages
Matija Hedl et al.
GASTROENTEROLOGY (2011)
The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes
Yun-Gi Kim et al.
IMMUNITY (2011)
Discovery of Salmonella Virulence Factors Translocated via Outer Membrane Vesicles to Murine Macrophages
Hyunjin Yoon et al.
INFECTION AND IMMUNITY (2011)
L-Ala-γ-D-Glu-meso-diaminopimelic Acid (DAP) Interacts Directly with Leucine-rich Region Domain of Nucleotide-binding Oligomerization Domain 1, Increasing Phosphorylation Activity of Receptor-interacting Serine/Threonine-protein Kinase 2 and Its Interaction with Nucleotide-binding Oligomerization Domain 1
Hamed Laroui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Distinct Roles for Nod2 Protein and Autocrine Interleukin-1β in Muramyl Dipeptide-induced Mitogen-activated Protein Kinase Activation and Cytokine Secretion in Human Macrophages
Matija Hedl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Muramyl Dipeptide Induces Th17 Polarization through Activation of Endothelial Cells
Michela Manni et al.
JOURNAL OF IMMUNOLOGY (2011)
Effects of NOD-like receptors in human B lymphocytes and crosstalk between NOD1/NOD2 and Toll-like receptors
Terese Petterson et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2011)
Non-apoptotic role of BID in inflammation and innate immunity
Garabet Yeretssian et al.
NATURE (2011)
Linear ubiquitination prevents inflammation and regulates immune signalling
Bjoern Gerlach et al.
NATURE (2011)
Defining the conserved internal architecture of a protein kinase
Alexandr P. Kornev et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells
Maria Kaparakis et al.
CELLULAR MICROBIOLOGY (2010)
ATG16L1 and NOD2 Interact in an Autophagy-Dependent Antibacterial Pathway Implicated in Crohn's Disease Pathogenesis
Craig R. Homer et al.
GASTROENTEROLOGY (2010)
Nucleotide-Binding Oligomerization Domain-2 Inhibits Toll-Like Receptor-4 Signaling in the Intestinal Epithelium
Ward M. Richardson et al.
GASTROENTEROLOGY (2010)
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses
Justine T. Tigno-Aranjuez et al.
GENES & DEVELOPMENT (2010)
Cell-Cell Propagation of NF-κB Transcription Factor and MAP Kinase Activation Amplifies Innate Immunity against Bacterial Infection
Christoph Alexander Kasper et al.
IMMUNITY (2010)
Muropeptides trigger distinct activation profiles in macrophages and dendritic cells
Mikhail V. Pashenkov et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2010)
Direct and Indirect Induction by 1,25-Dihydroxyvitamin D3 of the NOD2/CARD15-Defensin β2 Innate Immune Pathway Defective in Crohn Disease
Tian-Tian Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Synergism of NOD2 and NLRP3 activators promotes a unique transcriptional profile in murine dendritic cells
Cristina Conforti-Andreoni et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2010)
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
Leonardo H. Travassos et al.
NATURE IMMUNOLOGY (2010)
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
Rachel Cooney et al.
NATURE MEDICINE (2010)
Extracellular proteins secreted by probiotic bacteria as mediators of effects that promote mucosa-bacteria interactions
Borja Sanchez et al.
MICROBIOLOGY-SGM (2010)
The Inflammasomes: Guardians of the Body
Fablo Martinon et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
NOD-Like Receptors: Role in Innate Immunity and Inflammatory Disease
Grace Chen et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2009)
The distinct response of gamma delta T cells to the Nod2 agonist muramyl dipeptide
Hannah M. M. Kerns et al.
CELLULAR IMMUNOLOGY (2009)
ITCH K63-Ubiquitinates the NOD2 Binding Protein, RIP2, to Influence Inflammatory Signaling Pathways
MingFang Tao et al.
CURRENT BIOLOGY (2009)
Butyrate mediates nucleotide-binding and oligomerisation domain (NOD) 2-dependent mucosal immune responses against peptidoglycan
Chung-Hang Leung et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
Cellular Inhibitors of Apoptosis cIAP1 and cIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2
Mathieu J. M. Bertrand et al.
IMMUNITY (2009)
pH-dependent Internalization of Muramyl Peptides from Early Endosomes Enables Nod1 and Nod2 Signaling
Jooeun Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The Kinase Activity of Rip2 Determines Its Stability and Consequently Nod1-and Nod2-mediated Immune Responses
Chiara Nembrini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Clathrin- and Dynamin-Dependent Endocytic Pathway Regulates Muramyl Dipeptide Internalization and NOD2 Activation
Noemi Marina-Garcia et al.
JOURNAL OF IMMUNOLOGY (2009)
Large-scale Proteomics Analysis of the Human Kinome
Felix S. Oppermann et al.
MOLECULAR & CELLULAR PROTEOMICS (2009)
MECHANISMS OF DISEASE Inflammatory Bowel Disease
Clara Abraham et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
XIAP mediates NOD signaling via interaction with RIP2
Andreas Krieg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Engagement of NOD2 has a dual effect on proIL-1 beta mRNA transcription and secretion of bioactive IL-1 beta
Gerben Ferwerda et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals
Osamu Hitotsumatsu et al.
IMMUNITY (2008)
The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to toll-like receptor ligands
Yun-Gi Kim et al.
IMMUNITY (2008)
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor α (TNFα)-induced NF-κB activation
Eugene Varfolomeev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis
Tomohiro Watanabe et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via cryopyrin/NLRP3 independently of Nod2
Noemi Marina-Garcia et al.
JOURNAL OF IMMUNOLOGY (2008)
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle
Henrik Daub et al.
MOLECULAR CELL (2008)
The Nod-Like Receptor (NLR) Family: A Tale of Similarities and Differences
Martina Proell et al.
PLOS ONE (2008)
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide
Li-Chung Hsu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation
D. J. Mahoney et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Evidence for the involvement of NOD2 in regulating colonic epithelial cell growth and survival
Sheena M. Cruickshank et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2008)
The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction
Thomas A. Kufer et al.
CELLULAR MICROBIOLOGY (2008)
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-κB activation
Mizuho Hasegawa et al.
EMBO JOURNAL (2008)
TAK1 is a central mediator of NOD2 signaling in epidermal cells
Jae-Young Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2
Yibin Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Chronic stimulation of Nod2 mediates tolerance to bacterial products
Matija Hedl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Intracellular NOD-like receptors in host Defense and disease
Thirumala-Devi Kanneganti et al.
IMMUNITY (2007)
Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells
Jong-Hwan Park et al.
JOURNAL OF IMMUNOLOGY (2007)
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
A. Mayor et al.
CYTOKINE (2007)
Metabolic endotoxemia initiates obesity and insulin resistance
Patrice D. Cani et al.
DIABETES (2007)
Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines
Akiko Uehara et al.
MOLECULAR IMMUNOLOGY (2007)
SGT1 is essential for Nod1 activation
Jean da Silva Correia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Modulation of Nod2-dependent NF-κB signaling by the actin cytoskeleton
Sylvie Legrand-Poels et al.
JOURNAL OF CELL SCIENCE (2007)
RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs
Jong-Hwan Park et al.
JOURNAL OF IMMUNOLOGY (2007)
Solution structure of NOD1 CARD and mutational analysis of its interaction with the CARD of downstream kinase RICK
Florence Manon et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
hPepT1 selectively transports muramyl dipeptide but not Nod1-activating muramyl peptides
Manfred G. Ismair et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2006)
Identification of a regulatory autophosphorylation site in the serine-threonine kinase RIP2
Marion Dorsch et al.
CELLULAR SIGNALLING (2006)
Introduction to NF-κB:: players, pathways, perspectives
T. D. Gilmore
ONCOGENE (2006)
Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis
Tomohiro Watanabe et al.
IMMUNITY (2006)
Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-κB activation in muramyl dipeptide recognition
N Barnich et al.
JOURNAL OF CELL BIOLOGY (2005)
Structure of the apoptotic protease-activating factor 1 bound to ADP
SJ Riedl et al.
NATURE (2005)
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
KS Kobayashi et al.
SCIENCE (2005)
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
T Tanabe et al.
EMBO JOURNAL (2004)
RICK activates a NF-κB-dependent anti-human cytomegalovirus response
J Eickhoff et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains
A Kanayama et al.
MOLECULAR CELL (2004)
Regulation of IL-8 and IL-1β expression in Crohn's disease associated NOD2/CARD15 mutations
J Li et al.
HUMAN MOLECULAR GENETICS (2004)
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
T Watanabe et al.
NATURE IMMUNOLOGY (2004)
Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses
JS Damiano et al.
BIOCHEMICAL JOURNAL (2004)
hPepT1 transports muramyl dipeptide, activating NF-κB and stimulating IL-8 secretion in human colonic Caco2/bbe cells
SR Vavricka et al.
GASTROENTEROLOGY (2004)
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
J Viala et al.
NATURE IMMUNOLOGY (2004)
Activation signal of nuclear factor-κB in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2
M Kaneko et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2003)
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
M Chamaillard et al.
NATURE IMMUNOLOGY (2003)
Nod1 detects a unique muropeptide from Gram-negative bacterial peptidoglycan
SE Girardin et al.
SCIENCE (2003)
TNF-α and IFN-γ regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells
P Rosenstiel et al.
GASTROENTEROLOGY (2003)
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
SE Girardin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Host recognition of bacterial muramyl dipeptide mediated through NOD2
N Inohara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
K Kobayashi et al.
NATURE (2002)
The PYRIN domain: A member of the death domain-fold superfamily
WJ Fairbrother et al.
PROTEIN SCIENCE (2001)
CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
SE Girardin et al.
EMBO REPORTS (2001)
Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity
K Nickerson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
JP Hugot et al.
NATURE (2001)
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
Y Ogura et al.
NATURE (2001)
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-κB
Y Ogura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Human Nod1 confers responsiveness to bacterial lipopolysaccharides
N Inohara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)