相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cellular expression and function of naturally occurring variants of the human ABCG2 multidrug transporter
Boglarka Zambo et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2020)
CFTR modulator theratyping: Current status, gaps and future directions
John Paul Clancy et al.
JOURNAL OF CYSTIC FIBROSIS (2019)
Functional Characterization of Clinically-Relevant Rare Variants in ABCG2 Identified in a Gout and Hyperuricemia Cohort
Yu Toyoda et al.
CELLS (2019)
The eukaryotic linear motif resource-2018 update
Marc Gouw et al.
NUCLEIC ACIDS RESEARCH (2018)
Hyperuricemia enhances intracellular urate accumulation via down-regulation of cell-surface BCRP/ABCG2 expression in vascular endothelial cells
Hisakazu Komori et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2018)
UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
Vyacheslav Akimov et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
Vyacheslav Akimov et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Clinically relevant mutations in the ABCG2 transporter uncovered by genetic analysis linked to erythrocyte membrane protein expression
Boglarka Zambo et al.
SCIENTIFIC REPORTS (2018)
Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states
Ioannis Manolaridis et al.
NATURE (2018)
The where, what, and when of membrane protein degradation in neurons
Eugene Jennifer Jin et al.
DEVELOPMENTAL NEUROBIOLOGY (2018)
From the endoplasmic reticulum to the plasma membrane: mechanisms of CFTR folding and trafficking
Carlos M. Farinha et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
Jing Huang et al.
NATURE METHODS (2017)
ABCG2 loss-of-function polymorphism predicts poor response to allopurinol in patients with gout
R. L. Roberts et al.
PHARMACOGENOMICS JOURNAL (2017)
Functional Rescue of ABCC6 Deficiency by 4-Phenylbutyrate Therapy Reduces Dystrophic Calcification in Abcc6-/- Mice
Viola Pomozi et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2017)
Structure of the human multidrug transporter ABCG2
Nicholas M. I. . Taylor et al.
NATURE (2017)
Functional non-synonymous variants of ABCG2 and gout risk
Blanka Stiburkova et al.
RHEUMATOLOGY (2017)
A comprehensive analysis of the association of common variants of ABCG2 with gout
Kuang-Hui Yu et al.
SCIENTIFIC REPORTS (2017)
ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches
M. C. Cleophas et al.
PHARMACOGENOMICS & PERSONALIZED MEDICINE (2017)
Multiple common and rare variants of ABCG2 cause gout
Toshihide Higashino et al.
RMD OPEN (2017)
The linker region of breast cancer resistance protein ABCG2 is critical for coupling of ATP-dependent drug transport
S. Macalou et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Recent advances in the exploration of the bile salt export pump (BSEP/ABCB11) function
Agnes Telbisz et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2016)
The C421A (Q141K) polymorphism enhances the 3′-untranslated region (3′-UTR)-dependent regulation of ATP-binding cassette transporter ABCG2
Anne Ripperger et al.
BIOCHEMICAL PHARMACOLOGY (2016)
Functional characterization of the ABCG2 5′ non-coding exon variants: Stem cell specificity, translation efficiency and the influence of drug selection
Sara Sandor et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2016)
From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations
Gudio Veit et al.
MOLECULAR BIOLOGY OF THE CELL (2016)
The increasing complexity of the ubiquitin code
Richard Yau et al.
NATURE CELL BIOLOGY (2016)
Functional Rescue of Trafficking-Impaired ABCB4 Mutants by Chemical Chaperones
Raquel Gordo-Gilart et al.
PLOS ONE (2016)
Association Study of a Functional Variant on ABCG2 Gene with Sunitinib-Induced Severe Adverse Drug Reaction
Siew-Kee Low et al.
PLOS ONE (2016)
Targeted pharmacotherapy in progressive familial intrahepatic cholestasis type 2: Evidence for improvement of cholestasis with 4-phenylbutyrate
Emmanuel Gonzales et al.
HEPATOLOGY (2015)
JPred4: a protein secondary structure prediction server
Alexey Drozdetskiy et al.
NUCLEIC ACIDS RESEARCH (2015)
Expression of Tight Junction Components in Hepatocyte-Like Cells Differentiated from Human Embryonic Stem Cells
Boglarka Erdelyi-Belle et al.
PATHOLOGY & ONCOLOGY RESEARCH (2015)
CFTR: cystic fibrosis and beyond
Marcus A. Mall et al.
EUROPEAN RESPIRATORY JOURNAL (2014)
Functional Polymorphisms of the ABCG2 Gene Are Associated with Gout Disease in the Chinese Han Male Population
Danqiu Zhou et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
The relative frequency of CFTR mutation classes in European patients with cystic fibrosis
K. De Boeck et al.
JOURNAL OF CYSTIC FIBROSIS (2014)
Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling
Kirti Sharma et al.
CELL REPORTS (2014)
The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and drug transport by Pim-1-dependent and -independent mechanisms
Karthika Natarajan et al.
BIOCHEMICAL PHARMACOLOGY (2013)
GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit
Sander Pronk et al.
BIOINFORMATICS (2013)
International Transporter Consortium Commentary on Clinically Important Transporter Polymorphisms
K. M. Giacomini et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)
Dynamic ABCG2 expression in human embryonic stem cells provides the basis for stress response
Zsuzsa Erdei et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2013)
Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules
Owen M. Woodward et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Stimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters
Hugues de Boussac et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance
Karthika Natarajan et al.
BIOCHEMICAL PHARMACOLOGY (2012)
Histone Deacetylase Inhibitors Influence Chemotherapy Transport by Modulating Expression and Trafficking of a Common Polymorphic Variant of the ABCG2 Efflux Transporter
Agnes Basseville et al.
CANCER RESEARCH (2012)
Successful mutation-specific chaperone therapy with 4-phenylbutyrate in a child with progressive familial intrahepatic cholestasis type 2
Emmanuel Gonzales et al.
JOURNAL OF HEPATOLOGY (2012)
Proteomic Analyses Reveal Divergent Ubiquitylation Site Patterns in Murine Tissues
Sebastian A. Wagner et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
ABCG2 null alleles define the Jr(a-) blood group phenotype
Teresa Zelinski et al.
NATURE GENETICS (2012)
Expression Levels of the ABCG2 Multidrug Transporter in Human Erythrocytes Correspond to Pharmacologically Relevant Genetic Variations
Ildiko Kasza et al.
PLOS ONE (2012)
Individualized risk for statin-induced myopathy: current knowledge, emerging challenges and potential solutions
QiPing Feng et al.
PHARMACOGENOMICS (2012)
Decreased extra-renal urate excretion is a common cause of hyperuricemia
Kimiyoshi Ichida et al.
NATURE COMMUNICATIONS (2012)
Molecular chaperones as targets to circumvent the CFTR defect in cystic fibrosis
Rebecca A. Chanoux et al.
FRONTIERS IN PHARMACOLOGY (2012)
Rescue of ΔF508-CFTR Trafficking via a GRASP-Dependent Unconventional Secretion Pathway
Heon Yung Gee et al.
CELL (2011)
ABCC6 as a Target in Pseudoxanthoma Elasticum
Andras Varadi et al.
CURRENT DRUG TARGETS (2011)
Software News and Updates MDAnalysis: A Toolkit for the Analysis of Molecular Dynamics Simulations
Naveen Michaud-Agrawal et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)
A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells
Leslie M. Tompkins et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Dynamic vs Static ABCG2 Inhibitors to Sensitize Drug Resistant Cancer Cells
Hui Peng et al.
PLOS ONE (2010)
Evaluation of ABCG2 Expression in Human Embryonic Stem Cells: Crossing the Same River Twice?
Balazs Sarkadi et al.
STEM CELLS (2010)
Quality control of human ABCG2 protein in the endoplasmic reticulum: Ubliquitination and proteasomal degradation
Kanako Wakabayashi-Nakao et al.
ADVANCED DRUG DELIVERY REVIEWS (2009)
Arginine 383 is a crucial residue in ABCG2 biogenesis
Orsolya Polgar et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells
Anne-Marie Bleau et al.
CELL STEM CELL (2009)
Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2
Hiroshi Nakagawa et al.
FEBS JOURNAL (2009)
Major SNP (Q141K) Variant of Human ABC Transporter ABCG2 Undergoes Lysosomal and Proteasomal Degradations
Tomoka Furukawa et al.
PHARMACEUTICAL RESEARCH (2009)
Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simastatin
Jenni E. Keskitalo et al.
PHARMACOGENOMICS (2009)
High level functional expression of the ABCG2 multidrug transporter in undifferentiated human embryonic stem cells
Agota Apati et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)
The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox)
Gergely Szakacs et al.
DRUG DISCOVERY TODAY (2008)
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study
Abbas Dehghan et al.
LANCET (2008)
Breast cancer resistance protein (ABCG2) and drug disposition:: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe
Bradley L. Urquhart et al.
PHARMACOGENETICS AND GENOMICS (2008)
Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells
Honggang Wang et al.
MOLECULAR PHARMACOLOGY (2008)
The 44-kDa pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells
Yingqiu Xie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Targeted degradation of ABC transporters in health and disease
Daphne Nikles et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2007)
The effect of ABCG2 V12M, Q141K and Q126X, known functional variants in vitro, on the disposition of lamivudine
Ho-Sook Kim et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2007)
In and out of the ER: Protein folding, quality control, degradation, and related human diseases
Daniel N. Hebert et al.
PHYSIOLOGICAL REVIEWS (2007)
4-phenylbutyrate enhances the cell surface expression and the transport capacity of wild-type and mutated bile salt export pumps
Hisamitsu Hayashi et al.
HEPATOLOGY (2007)
The xenobiotic transporter ABCG2 plays a novel role in differentiation of trophoblast-like BeWo cells
D. A. Evseenko et al.
PLACENTA (2007)
Pharmacogenetics of ABCG2 and adverse reactions to gefitinib
George Cusatis et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
ATP-binding cassette transporter al modulates apolipoprotein A1 transcytosis through aortic endothelial cells
Clara Cavelier et al.
CIRCULATION RESEARCH (2006)
Role of BCRP 421C>A polymorphism on rosuvastatin pharynacokinetics in healthy Chinese males
Wei Zhang et al.
CLINICA CHIMICA ACTA (2006)
Novel 5′ untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues:: Implications for drug resistance, tissue-specific expression, and alternative promoter usage
T Nakanishi et al.
CANCER RESEARCH (2006)
The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins
AE van Herwaarden et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
Role of Cys-603 in dimer/oligomer formation of the breast cancer resistance protein BCRP/ABCG2
K Kage et al.
CANCER SCIENCE (2005)
Single nucleotide polymorphisms modify the transporter activity of ABCG2
K Morisaki et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2005)
Functional expression of ABCG2 transporter in human neural stem/progenitor cells
MO Islam et al.
NEUROSCIENCE RESEARCH (2005)
N-linked glycosylation of the human ABC transporter ABCG2 on asparagine 596 is not essential for expression, transport activity, or trafficking to the plasma membrane
NK Diop et al.
BIOCHEMISTRY (2005)
Two common PFIC2 mutations are associated with the impaired membrane trafficking of BSEP/ABCB11
H Hayashi et al.
HEPATOLOGY (2005)
Single nucleotide polymorphisms result in impaired membrane localization and reduced atpase activity in multidrug transporter ABCG2
S Mizuarai et al.
INTERNATIONAL JOURNAL OF CANCER (2004)
Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene
PLR Ee et al.
CANCER RESEARCH (2004)
Role of quality control pathways in human diseases involving protein misfolding
WJ Welch
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2004)
Intracellular trafficking of bile salt export pump (ABCB11) in polarized hepatic cells: Constitutive cycling between the canalicular membrane and Rab11-positive endosomes
Y Wakabayashi et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart
CM Martin et al.
DEVELOPMENTAL BIOLOGY (2004)
Functional analysis of SNPs variants of BCRP/ABCG2
C Kondo et al.
PHARMACEUTICAL RESEARCH (2004)
Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene
KJ Bailey-Dell et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2001)
Aggresomes, inclusion bodies and protein aggregation
RR Kopito
TRENDS IN CELL BIOLOGY (2000)
Modeling of loops in protein structures
A Fiser et al.
PROTEIN SCIENCE (2000)