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注意：仅列出部分参考文献，下载原文获取全部文献信息。Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model (vol 10, 1365, 2019)
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R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia
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Coding variants in TREM2 increase risk for Alzheimer's disease
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Margarita Giraldo et al.
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J Paloneva et al.
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J Paloneva et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2002)
Electrostatics of nanosystems: Application to microtubules and the ribosome
NA Baker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
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